LPXN

LPXN
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1X3H, 4XEF, 4XEK, 4XEV
Identifiers
Aliases	LPXN, LDPL, leupaxin
External IDs	OMIM: 605390; MGI: 2147677; HomoloGene: 3536; GeneCards: LPXN; OMA:LPXN - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	58,578,220 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	12,811,171 bp
RNA expression pattern
	Top expressed in
	thymus; ; granulocyte; ; mononuclear cell; ; monocyte; ; appendix; ; lymph node; ; blood; ; spleen; ; mucosa of ileum; ; epithelium of nasopharynx;
	Top expressed in
	mesenteric lymph nodes; ; spermatocyte; ; stroma of bone marrow; ; spleen; ; thymus; ; seminiferous tubule; ; blood; ; spermatid; ; medulla of thymus; ; subcutaneous adipose tissue;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; transcription coregulator activity; metal ion binding;
Cellular component	cytoplasm; perinuclear region of cytoplasm; podosome; cell junction; plasma membrane; cell projection; nucleus; focal adhesion; membrane; cytosol; nuclear speck;
Biological process	negative regulation of B cell receptor signaling pathway; negative regulation of cell adhesion; cell adhesion; regulation of cell adhesion mediated by integrin; regulation of transcription, DNA-templated; transcription, DNA-templated; signal transduction; protein-containing complex assembly; regulation of nucleic acid-templated transcription;
	Sources:Amigo / QuickGO
Orthologs
	9404
	107321
	ENSG00000110031
	ENSMUSG00000024696
	O60711
	Q99N69
	NM_001143995; NM_001307951; NM_004811
	NM_134152; NM_001361971
	NP_001137467; NP_001294880; NP_004802
	NP_598913; NP_001348900
	Wikidata
View/Edit Human	View/Edit Mouse

Leupaxin is a protein that in humans is encoded by the LPXN gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000110031 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000024696 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Lipsky BP, Beals CR, Staunton DE (Jun 1998). "Leupaxin is a novel LIM domain protein that forms a complex with PYK2". J Biol Chem. 273 (19): 11709–13. doi:10.1074/jbc.273.19.11709. PMID 9565592.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ "Entrez Gene: LPXN leupaxin".

References

Further reading