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Lim homeobox 9

From Wikipedia, the free encyclopedia
LHX9
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesLHX9, LIM homeobox 9
External IDsOMIM: 606066; MGI: 1316721; HomoloGene: 7816; GeneCards: LHX9; OMA:LHX9 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001014434
NM_020204
NM_001370213

NM_001025565
NM_001042577
NM_010714

RefSeq (protein)

NP_001014434
NP_064589
NP_001357142

NP_001020736
NP_001036042
NP_034844

Location (UCSC)Chr 1: 197.91 – 197.94 MbChr 1: 138.83 – 138.85 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

LIM homeobox 9 is a protein that in humans is encoded by the LHX9 gene.[5]

Function

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This gene encodes a member of the LIM homeobox gene family of developmentally expressed transcription factors. The encoded protein contains a homeodomain and two cysteine-rich zinc-binding LIM domains involved in protein-protein interactions. The protein is highly similar to a mouse protein that causes gonadal agenesis when inactivated, suggesting a role in gonadal development. Alternative splicing results in multiple transcript variants.

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000143355Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000019230Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: LIM homeobox 9".

Further reading

[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.