MAGI3

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MAGI3
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases MAGI3, MAGI-3, dJ730K3.2, membrane associated guanylate kinase, WW and PDZ domain containing 3
External IDs MGI: 1923484 HomoloGene: 26431 GeneCards: MAGI3
Gene location (Human)
Chromosome 1 (human)
Chr. Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for MAGI3
Genomic location for MAGI3
Band 1p13.2 Start 113,390,749 bp[1]
End 113,685,923 bp[1]
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001142782
NM_020965
NM_152900

NM_001159354
NM_133853

RefSeq (protein)

NP_001136254
NP_690864
NP_690864.2

NP_001152826
NP_598614

Location (UCSC) Chr 1: 113.39 – 113.69 Mb Chr 1: 104.01 – 104.22 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 is an enzyme that in humans is encoded by the MAGI3 gene.[5][6][7]


Interactions[edit]

MAGI3 has been shown to interact with PTPRB[8] and PTEN.[6]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000081026 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000052539 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Nagase T, Kikuno R, Nakayama M, Hirosawa M, Ohara O (Dec 2000). "Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (4): 273–81. doi:10.1093/dnares/7.4.271. PMID 10997877. 
  6. ^ a b Wu Y, Dowbenko D, Spencer S, Laura R, Lee J, Gu Q, Lasky LA (Aug 2000). "Interaction of the tumor suppressor PTEN/MMAC with a PDZ domain of MAGI3, a novel membrane-associated guanylate kinase". J Biol Chem. 275 (28): 21477–85. doi:10.1074/jbc.M909741199. PMID 10748157. 
  7. ^ "Entrez Gene: MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3". 
  8. ^ Adamsky, Konstantin; Arnold Katya; Sabanay Helena; Peles Elior (Apr 2003). "Junctional protein MAGI-3 interacts with receptor tyrosine phosphatase beta (RPTP beta) and tyrosine-phosphorylated proteins". J. Cell Sci. England. 116 (Pt 7): 1279–89. doi:10.1242/jcs.00302. ISSN 0021-9533. PMID 12615970. 

Further reading[edit]