MAGOH

MAGOH
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1P27, 2HYI, 2J0Q, 2J0S, 2XB2, 3EX7
Identifiers
Aliases	MAGOH, MAGOH1, MAGOHA, mago homolog, exon junction complex core component, mago homolog, exon junction complex subunit
External IDs	OMIM: 602603; MGI: 1330312; HomoloGene: 1776; GeneCards: MAGOH; OMA:MAGOH - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	53,238,518 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	107,744,621 bp
RNA expression pattern
	Top expressed in
	oocyte; ; secondary oocyte; ; monocyte; ; olfactory zone of nasal mucosa; ; rectum; ; mucosa of transverse colon; ; left lobe of thyroid gland; ; ventricular zone; ; body of uterus; ; granulocyte;
	Top expressed in
	zygote; ; secondary oocyte; ; yolk sac; ; epiblast; ; embryo; ; ventricular zone; ; embryo; ; placenta; ; morula; ; primary oocyte;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; RNA binding;
Cellular component	cytoplasm; nuclear speck; catalytic step 2 spliceosome; exon-exon junction complex; nucleoplasm; spliceosomal complex; nucleus;
Biological process	mRNA splicing, via spliceosome; termination of RNA polymerase II transcription; mRNA transport; mRNA processing; regulation of alternative mRNA splicing, via spliceosome; mRNA export from nucleus; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; mRNA 3'-end processing; regulation of translation; RNA splicing; RNA export from nucleus; transport;
	Sources:Amigo / QuickGO
Orthologs
	4116
	17149
	ENSG00000162385
	ENSMUSG00000028609
	P61326
	P61327
	NM_002370
	NM_001282737
	NP_002361
	NP_001269666
	Wikidata
View/Edit Human	View/Edit Mouse

Protein mago nashi homolog is a protein that in humans is encoded by the MAGOH gene.^[5]^[6]

Template:PBB Summary

Interactions

MAGOH has been shown to interact with RBM8A^[7]^[8] and NXF1.^[8]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000162385 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000028609 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Zhao XF, Colaizzo-Anas T, Nowak NJ, Shows TB, Elliott RW, Aplan PD (April 1998). "The mammalian homologue of mago nashi encodes a serum-inducible protein". Genomics. 47 (2): 319–22. doi:10.1006/geno.1997.5126. PMID 9479507.
^ "Entrez Gene: MAGOH mago-nashi homolog, proliferation-associated (Drosophila)".
^ Zhao, X F; Nowak N J; Shows T B; Aplan P D (January 2000). "MAGOH interacts with a novel RNA-binding protein". Genomics. 63 (1). UNITED STATES: 145–8. doi:10.1006/geno.1999.6064. ISSN 0888-7543. PMID 10662555. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help)
^ ^a ^b Kataoka, N; Diem M D; Kim V N; Yong J; Dreyfuss G (November 2001). "Magoh, a human homolog of Drosophila mago nashi protein, is a component of the splicing-dependent exon-exon junction complex". EMBO J. 20 (22). England: 6424–33. doi:10.1093/emboj/20.22.6424. ISSN 0261-4189. PMC 125744. PMID 11707413. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help)

Interactions

References

Further reading