MAK (gene)

MAK
Identifiers
Aliases	MAK, RP62, dJ417M14.2, male germ cell associated kinase
External IDs	OMIM: 154235; MGI: 96913; HomoloGene: 31344; GeneCards: MAK; OMA:MAK - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	10,838,553 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	41,233,182 bp
RNA expression pattern
	Top expressed in
	sperm; ; bronchial epithelial cell; ; right uterine tube; ; blood; ; caput epididymis; ; secondary oocyte; ; monocyte; ; palpebral conjunctiva; ; Achilles tendon; ; cerebellar vermis;
	Top expressed in
	spermatid; ; seminiferous tubule; ; spermatocyte; ; retinal pigment epithelium; ; outer nuclear layer; ; right lung lobe; ; respiratory epithelium; ; olfactory epithelium; ; pineal gland; ; utricle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; protein kinase activity; nucleotide binding; transcription coactivator activity; kinase activity; protein binding; ATP binding; metal ion binding; protein serine/threonine kinase activity;
Cellular component	centrosome; cell projection; photoreceptor inner segment; spindle; photoreceptor outer segment; microtubule organizing center; midbody; mitotic spindle; cytoskeleton; nucleus; cytoplasm; cilium; axoneme; motile cilium; photoreceptor connecting cilium; ciliary tip;
Biological process	cell differentiation; regulation of transcription, DNA-templated; phosphorylation; transcription, DNA-templated; multicellular organism development; protein phosphorylation; spermatogenesis; protein autophosphorylation; regulation of gene expression; intracellular signal transduction; intraciliary transport; cilium assembly; photoreceptor cell maintenance; negative regulation of non-motile cilium assembly; positive regulation of nucleic acid-templated transcription;
	Sources:Amigo / QuickGO
Orthologs
	4117
	17152
	ENSG00000111837
	ENSMUSG00000021363
	P20794
	Q04859
	NM_001242385; NM_001242957; NM_005906; NM_001377262
	NM_001145802; NM_001145803; NM_008547
	NP_001229314; NP_001229886; NP_005897; NP_001364191
	NP_001139274; NP_001139275; NP_032573
	Wikidata
View/Edit Human	View/Edit Mouse

Serine/threonine-protein kinase MAK is an enzyme that in humans is encoded by the MAK gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000111837 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000021363 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Ma AH, Xia L, Desai SJ, Boucher DL, Guan Y, Shih HM, Shi XB, deVere White RW, Chen HW, Tepper CG, Kung HJ (Sep 2006). "Male germ cell-associated kinase, a male-specific kinase regulated by androgen, is a coactivator of androgen receptor in prostate cancer cells". Cancer Res. 66 (17): 8439–47. doi:10.1158/0008-5472.CAN-06-1636. PMID 16951154.
^ "Entrez Gene: MAK male germ cell-associated kinase".

References

Further reading