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MAP4K3

From Wikipedia, the free encyclopedia
MAP4K3
Identifiers
AliasesMAP4K3, GLK, MAPKKKK3, MEKKK 3, MEKKK3, RAB8IPL1, mitogen-activated protein kinase kinase kinase kinase 3
External IDsOMIM: 604921; MGI: 2154405; HomoloGene: 2683; GeneCards: MAP4K3; OMA:MAP4K3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001270425
NM_003618

NM_001081357
NM_001290345
NM_001360278

RefSeq (protein)

NP_001257354
NP_003609

NP_001277274
NP_001347207

Location (UCSC)Chr 2: 39.25 – 39.44 MbChr 17: 80.58 – 80.73 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Mitogen-activated protein kinase kinase kinase kinase 3 is a protein that in humans is encoded by the MAP4K3 gene. [5]

Function

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This gene encodes a member of the mitogen-activated protein kinase kinase kinase kinase family. The encoded protein activates key effectors in cell signalling, among them c-Jun. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000011566Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024242Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Mitogen-activated protein kinase kinase kinase kinase 3". Retrieved 2017-09-22.

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.