MAP6

MAP6
Identifiers
Aliases	MAP6, MTAP6, N-STOP, STOP, MAP6-N, microtubule associated protein 6
External IDs	OMIM: 601783; MGI: 1201690; HomoloGene: 7850; GeneCards: MAP6; OMA:MAP6 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	75,669,038 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	98,986,344 bp
RNA expression pattern
	Top expressed in
	right frontal lobe; ; pituitary gland; ; bronchial epithelial cell; ; nucleus accumbens; ; ganglionic eminence; ; right uterine tube; ; Brodmann area 9; ; anterior pituitary; ; hypothalamus; ; caudate nucleus;
	Top expressed in
	neural layer of retina; ; visual cortex; ; superior frontal gyrus; ; lumbar spinal ganglion; ; primary visual cortex; ; pontine nuclei; ; dorsal tegmental nucleus; ; superior ganglion of vagus nerve; ; medial vestibular nucleus; ; arcuate nucleus;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; calmodulin binding; microtubule binding;
Cellular component	cytoplasm; perinuclear region of cytoplasm; Golgi apparatus; microtubule; cytoskeleton; membrane; axon; dendrite; transport vesicle membrane; cytoplasmic vesicle; cell projection; Golgi-associated vesicle; cis-Golgi network;
Biological process	lysosome localization; microtubule cytoskeleton organization; dendrite morphogenesis; cytoskeleton-dependent intracellular transport; positive regulation of axonogenesis; regulation of microtubule cytoskeleton organization;
	Sources:Amigo / QuickGO
Orthologs
	4135
	17760
	ENSG00000171533
	ENSMUSG00000055407
	Q96JE9
	Q7TSJ2
	NM_033063; NM_207577
	NM_001043355; NM_001048167; NM_010837
	NP_149052; NP_997460
	NP_001036820; NP_001041632; NP_034967
	Wikidata
View/Edit Human	View/Edit Mouse

Microtubule-associated protein 6 (MAP6) or stable tubule-only polypeptide (STOP or STOP protein) is a protein that in humans is encoded by the MAP6 gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000171533 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000055407 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Andrieux A, Salin PA, Vernet M, Kujala P, Baratier J, Gory-Faure S, Bosc C, Pointu H, Proietto D, Schweitzer A, Denarier E, Klumperman J, Job D (Sep 2002). "The suppression of brain cold-stable microtubules in mice induces synaptic defects associated with neuroleptic-sensitive behavioral disorders". Genes Dev. 16 (18): 2350–64. doi:10.1101/gad.223302. PMC 187434. PMID 12231625.
^ "Entrez Gene: MAP6 microtubule-associated protein 6".

References

Further reading