MEP1B

MEP1B
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4GWM, 4GWN
Identifiers
Aliases	MEP1B, meprin A subunit beta
External IDs	OMIM: 600389; MGI: 96964; HomoloGene: 48382; GeneCards: MEP1B; OMA:MEP1B - orthologs
Gene location (Human)
Chr.	Chromosome 18 (human)
End	32,220,404 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	21,233,256 bp
RNA expression pattern
	Top expressed in
	jejunal mucosa; ; mucosa of ileum; ; duodenum; ; mucosa of transverse colon; ; gonad; ; testicle; ; rectum; ; gastric mucosa; ; islet of Langerhans; ; smooth muscle tissue;
	Top expressed in
	ileum; ; jejunum; ; right kidney; ; duodenum; ; intestinal epithelium; ; human kidney; ; large intestine; ; colon; ; proximal tubule; ; Paneth cell;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	peptidase activity; metalloendopeptidase activity; protein binding; metallopeptidase activity; hydrolase activity; metal ion binding; identical protein binding; zinc ion binding;
Cellular component	integral component of membrane; extracellular region; membrane; plasma membrane; integral component of plasma membrane; meprin A complex;
Biological process	inflammatory response; toxin transport; proteolysis;
	Sources:Amigo / QuickGO
Orthologs
	4225
	17288
	ENSG00000141434
	ENSMUSG00000024313
	Q16820
	Q61847
	NM_001308171; NM_005925
	NM_008586
	NP_001295100; NP_005916
	NP_032612
	Wikidata
View/Edit Human	View/Edit Mouse

Meprin A subunit beta is a protein that in humans is encoded by the MEP1B gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000141434 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000024313 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Bond JS, Rojas K, Overhauser J, Zoghbi HY, Jiang W (Jul 1995). "The structural genes, MEP1A and MEP1B, for the alpha and beta subunits of the metalloendopeptidase meprin map to human chromosomes 6p and 18q, respectively". Genomics. 25 (1): 300–3. doi:10.1016/0888-7543(95)80142-9. PMID 7774936.
^ "Entrez Gene: MEP1B meprin A, beta".