MLSTD2

FAR1
Identifiers
Aliases	FAR1, MLSTD2, SDR10E1, PFCRD, fatty acyl-CoA reductase 1, CSPSD
External IDs	OMIM: 616107; MGI: 1914670; HomoloGene: 41718; GeneCards: FAR1; OMA:FAR1 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	13,732,346 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	113,170,718 bp
RNA expression pattern
	Top expressed in
	corpus callosum; ; jejunal mucosa; ; oral cavity; ; monocyte; ; spinal cord; ; C1 segment; ; rectum; ; bone marrow cells; ; subthalamic nucleus; ; inferior ganglion of vagus nerve;
	Top expressed in
	epithelium of stomach; ; pyloric antrum; ; granulocyte; ; transitional epithelium of urinary bladder; ; substantia nigra; ; mammillary body; ; proximal tubule; ; mucous cell of stomach; ; right kidney; ; cumulus cell;
	More reference expression data
	n/a
Gene ontology
Molecular function	fatty-acyl-CoA reductase (alcohol-forming) activity; oxidoreductase activity; alcohol-forming fatty acyl-CoA reductase activity;
Cellular component	integral component of membrane; peroxisomal membrane; peroxisome; peroxisomal matrix; membrane; integral component of peroxisomal membrane;
Biological process	glycerophospholipid biosynthetic process; long-chain fatty-acyl-CoA metabolic process; lipid metabolism; ether lipid biosynthetic process; wax biosynthetic process;
	Sources:Amigo / QuickGO
Orthologs
	84188
	67420
	ENSG00000197601
	ENSMUSG00000030759
	Q8WVX9
	Q922J9
	NM_032228
	NM_001285831; NM_026143; NM_027379; NM_001360668; NM_001360669
	NP_115604
	NP_001272760; NP_081655; NP_001347597; NP_001347598
	Wikidata
View/Edit Human	View/Edit Mouse

Fatty acyl-CoA reductase 1 is an enzyme that in humans is encoded by the FAR1 gene.^[5]^[6]^[7]^[8]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000197601 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000030759 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Cheng JB, Russell DW (Aug 2004). "Mammalian wax biosynthesis. I. Identification of two fatty acyl-Coenzyme A reductases with different substrate specificities and tissue distributions". J Biol Chem. 279 (36): 37789–97. doi:10.1074/jbc.M406225200. PMC 2757098. PMID 15220348.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ Cheng JB, Russell DW (Aug 2004). "Mammalian wax biosynthesis. II. Expression cloning of wax synthase cDNAs encoding a member of the acyltransferase enzyme family". J Biol Chem. 279 (36): 37798–807. doi:10.1074/jbc.M406226200. PMC 2743083. PMID 15220349.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ Persson B, Kallberg Y, Bray JE, Bruford E, Dellaporta SL, Favia AD, Duarte RG, Jornvall H, Kavanagh KL, Kedishvili N, Kisiela M, Maser E, Mindnich R, Orchard S, Penning TM, Thornton JM, Adamski J, Oppermann U (Feb 2009). "The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative". Chem Biol Interact. 178 (1–3): 94–8. doi:10.1016/j.cbi.2008.10.040. PMC 2896744. PMID 19027726.
^ "Entrez Gene: MLSTD2 male sterility domain containing 2".

References

Further reading