MMEL1

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MMEL1
Identifiers
AliasesMMEL1, MMEL2, NEP2, NEPII, NL1, NL2, SEP, membrane metallo-endopeptidase-like 1, membrane metalloendopeptidase like 1
External IDsMGI: 1351603 HomoloGene: 22778 GeneCards: MMEL1
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for MMEL1
Genomic location for MMEL1
Band1p36.32Start2,590,639 bp[1]
End2,633,016 bp[1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_033467

NM_013783

RefSeq (protein)

NP_258428

NP_038811

Location (UCSC)Chr 1: 2.59 – 2.63 MbChr 4: 154.87 – 154.9 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Membrane metallo-endopeptidase-like 1 is a protein that in humans is encoded by the MMEL1 gene.[5]

Function[edit]

The protein encoded by this gene is a member of the neutral endopeptidase (NEP) or membrane metallo-endopeptidase (MME) family. Family members play important roles in pain perception, arterial pressure regulation, phosphate metabolism and homeostasis. This protein is a type II transmembrane protein and is thought to be expressed as a secreted protein. This gene is expressed mainly in testis with weak expression in the brain, kidney, and heart.

References[edit]

  1. ^ a b c ENSG00000277131 GRCh38: Ensembl release 89: ENSG00000142606, ENSG00000277131 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000058183 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ "Entrez Gene: Membrane metallo-endopeptidase-like 1".

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.