MRPS9

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MRPS9
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesMRPS9, MRP-S9, RPMS9, S9mt, mitochondrial ribosomal protein S9
External IDsMGI: 1916777 HomoloGene: 32565 GeneCards: MRPS9
Gene location (Human)
Chromosome 2 (human)
Chr.Chromosome 2 (human)[1]
Chromosome 2 (human)
Genomic location for MRPS9
Genomic location for MRPS9
Band2q12.1Start105,038,069 bp[1]
End105,099,960 bp[1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_182640

NM_023514

RefSeq (protein)

NP_872578

NP_076003

Location (UCSC)Chr 2: 105.04 – 105.1 MbChr 1: 42.85 – 42.91 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Mitochondrial ribosomal protein S9 (MRPS9), otherwise known as uS9m, is a protein that in humans is encoded by the MRPS9 gene. [5]

Function[edit]

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. [provided by RefSeq, Jul 2008].

See also[edit]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000135972 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000060679 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ "Entrez Gene: Mitochondrial ribosomal protein S9". Retrieved 2018-02-11.

Further reading[edit]


This article incorporates text from the United States National Library of Medicine, which is in the public domain.