MX1

MX1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3LJB, 3SZR, 3ZYS, 4P4S, 4P4T, 4P4U
Identifiers
Aliases	MX1, IFI-78K, IFI78, MX, MxA, MX dynamin like GTPase 1, lncMX1-215
External IDs	OMIM: 147150; MGI: 97244; HomoloGene: 1844; GeneCards: MX1; OMA:MX1 - orthologs
Gene location (Human)
Chr.	Chromosome 21 (human)
End	41,470,071 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	97,362,100 bp
RNA expression pattern
	Top expressed in
	trigeminal ganglion; ; spinal ganglia; ; nasal epithelium; ; palpebral conjunctiva; ; monocyte; ; decidua; ; olfactory zone of nasal mucosa; ; granulocyte; ; spleen; ; human penis;
	Top expressed in
	embryo; ; surface ectoderm; ; duodenum; ; thymus; ; choroid plexus of fourth ventricle; ; yolk sac; ; muscle of thigh; ; liver; ; islet of Langerhans; ; perirhinal cortex;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; GTP binding; protein binding; GTPase activity; microtubule binding; identical protein binding;
Cellular component	cytoplasm; cytosol; nuclear membrane; endoplasmic reticulum membrane; membrane; endoplasmic reticulum; perinuclear region of cytoplasm; nucleus; mitochondrial membranes;
Biological process	defense response; immune system process; response to virus; type I interferon signaling pathway; innate immune response; signal transduction; apoptotic process; response to type I interferon; negative regulation of viral genome replication; mitochondrial fission; dynamin family protein polymerization involved in mitochondrial fission; membrane fusion; defense response to virus;
	Sources:Amigo / QuickGO
Orthologs
	4599
	17858
	ENSG00000157601
	ENSMUSG00000023341
	P20591
	Q9WVP9
	NM_001144925; NM_001178046; NM_001282920; NM_002462
	NM_013606
	NP_001138397; NP_001171517; NP_001269849; NP_002453
	NP_038634
	Wikidata
View/Edit Human	View/Edit Mouse

Interferon-induced GTP-binding protein Mx1 is a protein that in humans is encoded by the MX1 gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000157601 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000023341 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Haller O, Staeheli P, Kochs G (Jul 2007). "Interferon-induced Mx proteins in antiviral host defense". Biochimie. 89 (6–7): 812–8. doi:10.1016/j.biochi.2007.04.015. PMID 17570575.
^ "Entrez Gene: MX1 myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)".

References

Further reading