Mariano, as a surname, is of Italian, Spanish and Portuguese origin from the personal name Mariano, from the Latin family name Marianus (a derivative of the ancient personal name Marius, of Etruscan origin). In the early Christian era it came to be taken as an adjective derived from Maria, and was associated with the cult of the Virgin Mary. It was borne by various early saints, including a 3rd-century martyr in Numibia and a 5th-century hermit of Berry, France. It is also a Sephardic Jewish surname derived from the term Merano. The term, which is frequently derived from the New Testament phrase "maran atha" ("our Lord hath come"), denotes in Spanish "damned," "accursed," "banned"; also "hog," and in Portuguese it is used as an opprobrious epithet of the Jews because they do not eat pork. The name was applied to the Spanish Jews who, through compulsion or for form's sake, became converted to Christianity in consequence of the cruel persecutions of 1391 and of Vicente Ferrer's missionary sermons. These "conversos" (converts), as they were called in Spain, or "Christãos Novos" (Neo-Christians) in Portugal, or "Chuetas" in the Balearic Isles, or "Anusim" (constrained) in Hebrew, numbered more than 100,000. With them the history of the Pyrenean Peninsula, and indirectly that of the Jews also, enters upon a new phase; for they were the immediate cause both of the introduction of the Inquisition into Spain and of the expulsion of the Jews from that country.
- Mariano Azuela, Mexican writer
- Mariano Baracetti, Argentine beach volleyball player
- Mariano Duncan, baseball player and coach
- Mariano Egaña, Chilean lawyer and politician
- Mariano Ferreira Filho, Brazilian soccer player
- Mariano Frumboli, Argentine tango dancer
- Mariano González, Argentine football (soccer) player
- Mariano Grondona, Argentine journalist
- Mariano Hoyas, Spanish football (soccer) player
- Mariano Iberico Rodríguez, Peruvian philosopher
- Mariano Martínez, Argentine actor and model
- Mariano Marquez, Puerto Rican boxer
- Mariano Díaz Mejía, Dominican football player
- Mariano Moreno, Argentine national hero
- Mariano Mores, Argentine tango pianist and composer
- Mariano Petit de Murat, Mexican digital and contemporary artist
- Mariano Rampolla, Italian cardinal
- Mariano Rivera, baseball player
- Mariano Rajoy, Spanish politician, prime minister of Spain
- Mariano Scartezzini, Italian long-distance runner
- Mariano Torres, Argentine football (soccer) player
- Mariano Trías, Filipino vice president of the brief Republic of Biak-na-Bato
- Mariano Trípodi, Argentine football (soccer) player
- Mariano Vallejo, Californian politician, military commander, and rancher
- Mariano Zabaleta, Argentine tennis player
- Charlie Mariano, American jazz musician
- Bob Mariano, American corporate executive
- Eleanor Concepcion Mariano, also known as Connie Mariano, former White House physician
- Jarah Mariano, American model
- Josell Mariano, an American actor
- Jess Mariano, a fictional character from Gilmore Girls
- Guy Mariano, professional skateboarder
- Luis Mariano, Spanish-French singer
- Otacílio Mariano Neto (born 1982), Brazilian footballer
- Nelson Mariano II, chess grandmaster
- Rob Mariano, American television personality
- Sivan Mariano, contestant on cycle 1 of Israel's Next Top Model
- Ian Mariano, a Guamanian international footballer
- Marianopolis College, often nicknamed Mariano
- Campbell, Mike. "Meaning, origin and history of the name Mariano".
- Campbell, Mike. "Meaning, origin and history of the name Marianus".
- Campbell, Mike. "Meaning, origin and history of the name Marius".
- Campbell, Mike. "Behind the Name: View Name".
- "Mariano Name Meaning & Mariano Family History at Ancestry.com".
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