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NAPG

From Wikipedia, the free encyclopedia
NAPG
Identifiers
AliasesNAPG, GAMMASNAP, NSF attachment protein gamma
External IDsOMIM: 603216; MGI: 104561; HomoloGene: 2838; GeneCards: NAPG; OMA:NAPG - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_003826

NM_028017

RefSeq (protein)

NP_003817

NP_082293

Location (UCSC)Chr 18: 10.53 – 10.55 MbChr 18: 63.11 – 63.13 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Gamma-soluble NSF attachment protein is a SNAP protein that in humans is encoded by the NAPG gene.[5][6]

Function

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NSF and SNAPs (NSF attachment proteins) are general elements of the cellular membrane transport apparatus. The sequence of the predicted 312-amino acid human protein encoded by NAPG is 95% identical to that of bovine gamma-SNAP. NAPG mediates platelet exocytosis and controls the membrane fusion events of this process.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000134265Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024581Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Lemons PP, Chen D, Bernstein AM, Bennett MK, Whiteheart SW (Sep 1997). "Regulated secretion in platelets: identification of elements of the platelet exocytosis machinery". Blood. 90 (4): 1490–500. doi:10.1182/blood.V90.4.1490. PMID 9269766.
  6. ^ a b "Entrez Gene: NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma".

Further reading

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