NDUFC2

NDUFC2
Identifiers
Aliases	NDUFC2, B14.5b, CI-B14.5b, HLC-1, NADHDH2, NADH:ubiquinone oxidoreductase subunit C2, MC1DN36
External IDs	OMIM: 603845; MGI: 1344370; HomoloGene: 3344; GeneCards: NDUFC2; OMA:NDUFC2 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	78,079,862 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	97,057,009 bp
RNA expression pattern
	Top expressed in
	right adrenal gland; ; left adrenal cortex; ; right adrenal cortex; ; muscle of thigh; ; mucosa of transverse colon; ; olfactory zone of nasal mucosa; ; buccal mucosa cell; ; right lobe of thyroid gland; ; left lobe of thyroid gland; ; ganglionic eminence;
	Top expressed in
	facial motor nucleus; ; atrioventricular valve; ; endocardial cushion; ; medial ganglionic eminence; ; anterior horn of spinal cord; ; intercostal muscle; ; digastric muscle; ; brown adipose tissue; ; lobe of cerebellum; ; mammillary body;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	NADH dehydrogenase (ubiquinone) activity;
Cellular component	cytoplasm; integral component of membrane; mitochondrial inner membrane; mitochondrial respiratory chain complex I; respirasome; membrane; mitochondrion; plasma membrane; azurophil granule membrane;
Biological process	mitochondrial electron transport, NADH to ubiquinone; neutrophil degranulation; mitochondrial respiratory chain complex I assembly;
	Sources:Amigo / QuickGO
Orthologs
	4718
	68197
	ENSG00000151366
	ENSMUSG00000030647
	O95298
	Q9CQ54
	NM_004549; NM_001204054; NM_001204055
	NM_024220
	NP_001190983; NP_001190984; NP_004540
	NP_077182
	Wikidata
View/Edit Human	View/Edit Mouse

NADH dehydrogenase [ubiquinone] 1 subunit C2 is an enzyme that in humans is encoded by the NDUFC2 gene.^[5]^[6]

The NDUF2 gene encodes one of the subunits of complex I, the first and largest complex of the mitochondrial respiratory chain.^[5]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000151366 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000030647 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b Loeffen JL, Triepels RH, van den Heuvel LP, Schuelke M, Buskens CA, Smeets RJ, Trijbels JM, Smeitink JA (Jan 1999). "cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed". Biochem Biophys Res Commun. 253 (2): 415–22. doi:10.1006/bbrc.1998.9786. PMID 9878551.
^ "Entrez Gene: NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa".

References

Further reading