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NOX1

From Wikipedia, the free encyclopedia
NOX1
Identifiers
AliasesNOX1, GP91-2, MOX1, NOH-1, NOH1, NADPH oxidase 1, NOH-1L
External IDsOMIM: 300225; MGI: 2450016; HomoloGene: 48495; GeneCards: NOX1; OMA:NOX1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_013955
NM_001271815
NM_007052
NM_013954

NM_172203

RefSeq (protein)

NP_001258744
NP_008983
NP_039249

NP_757340

Location (UCSC)Chr X: 100.84 – 100.87 MbChr X: 132.99 – 133.12 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

NADPH oxidase 1 is an enzyme that in humans is encoded by the NOX1 gene.[5]

NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox. Two transcript variants encoding different isoforms have been found for this gene.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000007952Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000031257Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Suh YA, Arnold RS, Lassegue B, Shi J, Xu X, Sorescu D, Chung AB, Griendling KK, Lambeth JD (Sep 1999). "Cell transformation by the superoxide-generating oxidase Mox1". Nature. 401 (6748): 79–82. Bibcode:1999Natur.401...79S. doi:10.1038/43459. PMID 10485709. S2CID 4365361.
  6. ^ "Entrez Gene: NOX1 NADPH oxidase 1".

Further reading

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