NRXN3

NRXN3
Identifiers
Aliases	NRXN3, C14orf60, neurexin 3
External IDs	OMIM: 600567; MGI: 1096389; GeneCards: NRXN3; OMA:NRXN3 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	79,868,291 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	90,334,935 bp
RNA expression pattern
	Top expressed in
	cerebellar vermis; ; pars compacta; ; pars reticulata; ; pons; ; Brodmann area 23; ; cerebellar hemisphere; ; right hemisphere of cerebellum; ; middle temporal gyrus; ; superior vestibular nucleus; ; external globus pallidus;
	Top expressed in
	Rostral migratory stream; ; lateral septal nucleus; ; piriform cortex; ; lobe of cerebellum; ; cerebellar vermis; ; lateral geniculate nucleus; ; medial geniculate nucleus; ; anterior amygdaloid area; ; lateral hypothalamus; ; nucleus accumbens;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	neuroligin family protein binding; transmembrane signaling receptor activity; cell adhesion molecule binding; metal ion binding; signaling receptor activity;
Cellular component	integral component of membrane; membrane; plasma membrane; integral component of plasma membrane;
Biological process	neuron cell-cell adhesion; social behavior; vocalization behavior; adult behavior; cell adhesion; learning; angiogenesis; signal transduction; axon guidance; positive regulation of synapse assembly; positive regulation of synapse maturation; synapse assembly; neurotransmitter secretion; chemical synaptic transmission;
	Sources:Amigo / QuickGO
Orthologs
	9369
	18191
	ENSG00000021645
	ENSMUSG00000066392
	Q9HDB5
	Q6P9K9; Q8C985
NM_001105250; NM_001272020; NM_004796; NM_138970; NM_001330195;
	NM_001366425; NM_001366426
	NM_001198587; NM_001252074; NM_172544
NP_001098720; NP_001258949; NP_001317124; NP_004787; NP_620426;
	NP_001353354; NP_001353355; NP_004787.2
	NP_001185516; NP_001239003; NP_766132; NP_001239003.1
	Wikidata
View/Edit Human	View/Edit Mouse

Neurexin-3-alpha is a protein that in humans is encoded by the NRXN3 gene.^[5]^[6]^[7]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000021645 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000066392 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Rowen L, Young J, Birditt B, Kaur A, Madan A, Philipps DL, Qin S, Minx P, Wilson RK, Hood L, Graveley BR (Apr 2002). "Analysis of the human neurexin genes: alternative splicing and the generation of protein diversity". Genomics. 79 (4): 587–97. doi:10.1006/geno.2002.6734. PMID 11944992.
^ Occhi G, Rampazzo A, Beffagna G, Antonio Danieli G (Oct 2002). "Identification and characterization of heart-specific splicing of human neurexin 3 mRNA (NRXN3)". Biochem Biophys Res Commun. 298 (1): 151–5. doi:10.1016/S0006-291X(02)02403-8. PMID 12379233.
^ "Entrez Gene: NRXN3 neurexin 3".

References

Further reading