NSL1

NSL1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4NF9
Identifiers
Aliases	NSL1, C1orf48, MIS14, DC8, MIS12 kinetochore complex component, NSL1 component of MIS12 kinetochore complex
External IDs	OMIM: 609174; MGI: 2685830; HomoloGene: 22898; GeneCards: NSL1; OMA:NSL1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	212,791,782 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	190,818,671 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; optic nerve; ; germinal epithelium; ; Epithelium of choroid plexus; ; hair follicle; ; tibia; ; inferior ganglion of vagus nerve; ; trabecular bone; ; kidney tubule; ; parietal pleura;
	Top expressed in
	hand; ; yolk sac; ; epiblast; ; primitive streak; ; ventricular zone; ; spermatocyte; ; embryo; ; tail of embryo; ; cumulus cell; ; thymus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	MIS12/MIND type complex; chromosome, centromeric region; nucleus; kinetochore; chromosome; nucleoplasm; nuclear speck; cytosol;
Biological process	cell division; cell cycle; chromosome segregation; mitotic sister chromatid segregation;
	Sources:Amigo / QuickGO
Orthologs
	25936
	381318
	ENSG00000117697
	ENSMUSG00000062510
	Q96IY1
	Q8K305
	NM_015471; NM_001042549; NM_001297736; NM_001297737; NM_001297739
	NM_198654
	NP_001036014; NP_001284665; NP_001284666; NP_001284668; NP_056286
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Kinetochore-associated protein NSL1 homolog is a protein that in humans is encoded by the NSL1 gene.^[5]

Interactions

NSL1 has been shown to interact with MIS12^[6] and DSN1.^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000117697 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000062510 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: NSL1 NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)".
^ ^a ^b Obuse, Chikashi; Iwasaki Osamu; Kiyomitsu Tomomi; Goshima Gohta; Toyoda Yusuke; Yanagida Mitsuhiro (Nov 2004). "A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1". Nat. Cell Biol. 6 (11). England: 1135–41. doi:10.1038/ncb1187. ISSN 1465-7392. PMID 15502821. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help)