Neocosmospora

Neocosmospora
Scientific classification
Kingdom:	Fungi
Division:	Ascomycota
Subdivision:	Pezizomycotina
Class:	Sordariomycetes
Order:	Hypocreales
Family:	Nectriaceae
Genus:	Neocosmospora; E.F. Sm. 1899
Species
	See text.

Neocosmospora is a genus of fungi in the Nectriaceae family.

Species

Bioassay-guided fractionation of a fungus Neocosmospora sp. resulted in the isolation of three new resorcylic acid lactones, neocosmosin A (2), neocosmosin B (3) and neocosmosin C (4). Three known resorcylic acid lactones, monocillin IV (1), monocillin II (5) and radicicol (6) were also isolated and identified, where compounds 4–6 show good binding affinity for the human opioid receptors. These findings have important implications for the potential psychoactive effects with this class of compounds.^[1]

References

^ Gao J, Radwan MM, León F, Dale OR, Husni AS, Wu Y, Lupien S, Wang X, Manly SP, Hill RA, Dugan FM, Cutler HG, Cutler SJ (May 2013). "Neocosmospora sp.-derived resorcylic acid lactones with in vitro binding affinity for human opioid and cannabinoid receptors". Journal of Natural Products. 76 (5): 824–8. doi:10.1021/np300653d. PMC 3723356. PMID 23659286.

External links

Neocosmospora in Index Fungorum

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[1] Gao J, Radwan MM, León F, Dale OR, Husni AS, Wu Y, Lupien S, Wang X, Manly SP, Hill RA, Dugan FM, Cutler HG, Cutler SJ (May 2013). "Neocosmospora sp.-derived resorcylic acid lactones with in vitro binding affinity for human opioid and cannabinoid receptors". Journal of Natural Products. 76 (5): 824–8. doi:10.1021/np300653d. PMC 3723356. PMID 23659286.

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