ORAI2

ORAI2
Identifiers
Aliases	ORAI2, C7orf19, CBCIP2, MEM142B, TMEM142B, ORAI calcium release-activated calcium modulator 2
External IDs	OMIM: 610929; MGI: 2443195; HomoloGene: 32799; GeneCards: ORAI2; OMA:ORAI2 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	102,456,825 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	136,199,567 bp
RNA expression pattern
	Top expressed in
	renal medulla; ; ventral tegmental area; ; pylorus; ; superior vestibular nucleus; ; nipple; ; inferior ganglion of vagus nerve; ; superior surface of tongue; ; trigeminal ganglion; ; pericardium; ; subthalamic nucleus;
	Top expressed in
	dentate gyrus; ; hippocampus proper; ; superior frontal gyrus; ; piriform cortex; ; thymus; ; olfactory tubercle; ; cerebellar cortex; ; molar; ; lip; ; blood;
	More reference expression data
	n/a
Gene ontology
Molecular function	store-operated calcium channel activity; protein binding;
Cellular component	growth cone; integral component of membrane; membrane;
Biological process	store-operated calcium entry; calcium ion transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	80228
	269717
	ENSG00000160991
	ENSMUSG00000039747
	Q96SN7
	Q8BH10
	NM_032831; NM_001126340; NM_001271818; NM_001271819
	NM_178751
	NP_001119812; NP_001258747; NP_001258748; NP_116220
	NP_848866
	Wikidata
View/Edit Human	View/Edit Mouse

Protein orai-2 is a protein that in humans is encoded by the ORAI2 gene.^[5]^[6] Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000160991 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000039747 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Feske S, Gwack Y, Prakriya M, Srikanth S, Puppel SH, Tanasa B, Hogan PG, Lewis RS, Daly M, Rao A (May 2006). "A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function". Nature. 441 (7090): 179–85. doi:10.1038/nature04702. PMID 16582901.
^ "Entrez Gene: TMEM142B transmembrane protein 142B".