PCDH17

PCDH17
Identifiers
Aliases	PCDH17, PCDH68, PCH68, protocadherin 17
External IDs	OMIM: 611760; MGI: 2684924; HomoloGene: 8700; GeneCards: PCDH17; OMA:PCDH17 - orthologs
Gene location (Human)
Chr.	Chromosome 13 (human)
End	57,729,311 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	84,776,442 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; visceral pleura; ; sperm; ; Brodmann area 23; ; entorhinal cortex; ; lower lobe of lung; ; pars reticulata; ; superior vestibular nucleus; ; germinal epithelium; ; ventral tegmental area;
	Top expressed in
	lateral hypothalamus; ; ventromedial nucleus; ; dorsomedial hypothalamic nucleus; ; anterior amygdaloid area; ; mammillary body; ; lateral septal nucleus; ; paraventricular nucleus of hypothalamus; ; ventral tegmental area; ; arcuate nucleus; ; supraoptic nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	calcium ion binding; protein binding;
Cellular component	integral component of membrane; plasma membrane; membrane; integral component of plasma membrane; glutamatergic synapse; GABA-ergic synapse; integral component of postsynaptic membrane; integral component of presynaptic membrane;
Biological process	presynaptic active zone assembly; adult behavior; regulation of synaptic vesicle clustering; negative regulation of synaptic transmission; homophilic cell adhesion via plasma membrane adhesion molecules; cell adhesion; cell-cell signaling; synapse assembly; synaptic membrane adhesion;
	Sources:Amigo / QuickGO
Orthologs
	27253
	219228
	ENSG00000118946
	ENSMUSG00000035566
	O14917
	n/a
	NM_001040429; NM_014459
	NM_001013753
	NP_001035519
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Protocadherin-17 is a protein that in humans is encoded by the PCDH17 gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000118946 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000035566 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Nollet F, Kools P, van Roy F (Jul 2000). "Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members". J Mol Biol. 299 (3): 551–72. doi:10.1006/jmbi.2000.3777. PMID 10835267.
^ "Entrez Gene: PCDH17 protocadherin 17".

References

Further reading