PCDH8

PCDH8
Identifiers
Aliases	PCDH8, ARCADLIN, PAPC, protocadherin 8
External IDs	OMIM: 603580; MGI: 1306800; HomoloGene: 1943; GeneCards: PCDH8; OMA:PCDH8 - orthologs
Gene location (Human)
Chr.	Chromosome 13 (human)
End	52,848,641 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	80,008,752 bp
RNA expression pattern
	Top expressed in
	Brodmann area 23; ; frontal pole; ; endothelial cell; ; middle temporal gyrus; ; Brodmann area 10; ; dorsolateral prefrontal cortex; ; primary visual cortex; ; Brodmann area 9; ; superior frontal gyrus; ; nucleus accumbens;
	Top expressed in
	anterior amygdaloid area; ; lateral septal nucleus; ; substantia nigra; ; subiculum; ; Region I of hippocampus proper; ; superior colliculus; ; dorsomedial hypothalamic nucleus; ; ventral tegmental area; ; paraventricular nucleus of hypothalamus; ; lateral hypothalamus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	calcium ion binding;
Cellular component	cell projection; cell junction; postsynaptic membrane; plasma membrane; membrane; presynaptic membrane; integral component of membrane; synapse; dendrite; integral component of plasma membrane; glutamatergic synapse; integral component of postsynaptic membrane;
Biological process	morphogenesis of embryonic epithelium; somitogenesis; chemical synaptic transmission; homophilic cell adhesion via plasma membrane adhesion molecules; cell-cell signaling; cell adhesion; nervous system development; regulation of synaptic membrane adhesion;
	Sources:Amigo / QuickGO
Orthologs
	5100
	18530
	ENSG00000136099
	ENSMUSG00000036422
	O95206
	Q7TSK3
	NM_032949; NM_002590
	NM_001042726; NM_021543
	NP_002581; NP_116567
	NP_001036191; NP_067518
	Wikidata
View/Edit Human	View/Edit Mouse

Protocadherin-8 is a protein that in humans is encoded by the PCDH8 gene.^[5]^[6]^[7]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000136099 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000036422 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Strehl S, Glatt K, Liu QM, Glatt H, Lalande M (Dec 1998). "Characterization of two novel protocadherins (PCDH8 and PCDH9) localized on human chromosome 13 and mouse chromosome 14". Genomics. 53 (1): 81–9. doi:10.1006/geno.1998.5467. PMID 9787079.
^ Strehl S, LaSalle JM, Lalande M (Oct 1997). "High-resolution analysis of DNA replication domain organization across an R/G-band boundary". Mol Cell Biol. 17 (10): 6157–66. PMC 232466. PMID 9315676.
^ "Entrez Gene: PCDH8 protocadherin 8".

References

Further reading