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PCID2

From Wikipedia, the free encyclopedia
PCID2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesPCID2, F10, PCI domain containing 2
External IDsOMIM: 613713; MGI: 2443003; HomoloGene: 10168; GeneCards: PCID2; OMA:PCID2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_178708

RefSeq (protein)

NP_848823

Location (UCSC)Chr 13: 113.18 – 113.21 MbChr 8: 13.13 – 13.16 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

PCI domain containing 2 is a protein that in humans is encoded by the PCID2 gene. [5]

Function

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This gene encodes a component of the TREX-2 complex (transcription and export complex 2), which regulates mRNA export from the nucleus. This protein regulates expression of Mad2 mitotic arrest deficient-like 1, a cell division checkpoint protein. This protein also interacts with and stabilizes Brca2 (breast cancer 2) protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016].

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000126226Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000038542Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: PCI domain containing 2". Retrieved 2017-12-13.

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.