PIB5PA

INPP5J
Identifiers
Aliases	INPP5J, INPP5, PIB5PA, PIPP, inositol polyphosphate-5-phosphatase J
External IDs	OMIM: 606481; MGI: 2158663; HomoloGene: 8682; GeneCards: INPP5J; OMA:INPP5J - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	31,134,697 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	3,504,821 bp
RNA expression pattern
	Top expressed in
	right lobe of thyroid gland; ; left lobe of thyroid gland; ; right hemisphere of cerebellum; ; mucosa of transverse colon; ; parotid gland; ; apex of heart; ; right auricle; ; left ventricle; ; duodenum; ; body of pancreas;
	Top expressed in
	cerebellar cortex; ; submandibular gland; ; primary visual cortex; ; CA3 field; ; superior frontal gyrus; ; perirhinal cortex; ; entorhinal cortex; ; dentate gyrus of hippocampal formation granule cell; ; masseter muscle; ; medulla oblongata;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	SH3 domain binding; inositol-polyphosphate 5-phosphatase activity; protein binding; hydrolase activity; phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity; inositol-1,4,5-trisphosphate 5-phosphatase activity; inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity;
Cellular component	cytoplasm; ruffle; growth cone; dendritic shaft; cytosol; plasma membrane;
Biological process	phosphatidylinositol biosynthetic process; negative regulation of neuron projection development; inositol phosphate metabolic process; negative regulation of microtubule polymerization; phosphatidylinositol dephosphorylation; negative regulation of peptidyl-serine phosphorylation; inositol phosphate dephosphorylation;
	Sources:Amigo / QuickGO
Orthologs
	27124
	170835
	ENSG00000185133
	ENSMUSG00000034570
	Q15735
	P59644
NM_001002837; NM_001284285; NM_001284286; NM_001284287; NM_001284288;
	NM_001284289; NM_014422
	NM_172439
NP_001002837; NP_001271214; NP_001271215; NP_001271216; NP_001271217;
	NP_001271218
	NP_766027
	Wikidata
View/Edit Human	View/Edit Mouse

Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A is an enzyme that in humans is encoded by the INPP5J gene.^[5]^[6] Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000185133 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000034570 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Dunham I, Shimizu N, Roe BA, Chissoe S, Hunt AR, Collins JE, Bruskiewich R, Beare DM, Clamp M, Smink LJ, Ainscough R, Almeida JP, Babbage A, Bagguley C, Bailey J, Barlow K, Bates KN, Beasley O, Bird CP, Blakey S, Bridgeman AM, Buck D, Burgess J, Burrill WD, O'Brien KP, et al. (Dec 1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489–95. doi:10.1038/990031. PMID 10591208.
^ "Entrez Gene: PIB5PA phosphatidylinositol (4,5) bisphosphate 5-phosphatase, A".

References

Further reading