PLXND1

PLXND1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3H6N
Identifiers
Aliases	PLXND1, PLEXD1, plexin D1
External IDs	OMIM: 604282; MGI: 2154244; HomoloGene: 22866; GeneCards: PLXND1; OMA:PLXND1 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	129,606,676 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	115,971,966 bp
RNA expression pattern
	Top expressed in
	upper lobe of left lung; ; right coronary artery; ; right lung; ; tibial nerve; ; canal of the cervix; ; apex of heart; ; body of uterus; ; left uterine tube; ; gallbladder; ; left coronary artery;
	Top expressed in
	thymus; ; external carotid artery; ; ankle joint; ; molar; ; lumbar spinal ganglion; ; internal carotid artery; ; yolk sac; ; atrium; ; genital tubercle; ; decidua;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein domain specific binding; protein binding; semaphorin receptor activity;
Cellular component	integral component of membrane; membrane; plasma membrane; lamellipodium; integral component of plasma membrane; lamellipodium membrane; cell projection; semaphorin receptor complex;
Biological process	cardiac septum development; outflow tract morphogenesis; regulation of angiogenesis; coronary vasculature development; multicellular organism development; aorta development; angiogenesis; dichotomous subdivision of terminal units involved in salivary gland branching; branching involved in blood vessel morphogenesis; synapse assembly; positive regulation of protein binding; endothelial cell migration; semaphorin-plexin signaling pathway; signal transduction; negative regulation of cell adhesion; regulation of cell shape; regulation of cell migration; positive regulation of axonogenesis; regulation of GTPase activity; positive regulation of transcription of Notch receptor target; semaphorin-plexin signaling pathway involved in axon guidance;
	Sources:Amigo / QuickGO
Orthologs
	23129
	67784
	ENSG00000004399
	ENSMUSG00000030123
	Q9Y4D7
	Q3UH93
	NM_015103
	NM_026376
	NP_055918
	NP_080652
	Wikidata
View/Edit Human	View/Edit Mouse

Plexin-D1 is a protein that in humans is encoded by the PLXND1 gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000004399 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000030123 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ van der Zwaag B, Hellemons AJ, Leenders WP, Burbach JP, Brunner HG, Padberg GW, Van Bokhoven H (Nov 2002). "PLEXIN-D1, a novel plexin family member, is expressed in vascular endothelium and the central nervous system during mouse embryogenesis". Dev Dyn. 225 (3): 336–43. doi:10.1002/dvdy.10159. PMID 12412018.
^ "Entrez Gene: PLXND1 plexin D1".

References

Further reading