POLR3C

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POLR3C
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases POLR3C, RPC3, RPC62, polymerase (RNA) III subunit C
External IDs MGI: 1921664 HomoloGene: 38185 GeneCards: POLR3C
RNA expression pattern
PBB GE POLR3C 210573 s at fs.png

PBB GE POLR3C 209382 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001303456
NM_006468

NM_028925

RefSeq (protein)

NP_001290385
NP_006459

NP_083201.1
NP_083201

Location (UCSC) Chr 1: 145.82 – 145.84 Mb Chr 3: 96.71 – 96.73 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

DNA-directed RNA polymerase III subunit RPC3 is an enzyme that in humans is encoded by the POLR3C gene.[3][4][5]


Interactions[edit]

POLR3C has been shown to interact with GTF3C4.[6][7]

Related gene problems[edit]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Wang Z, Roeder RG (Jun 1997). "Three human RNA polymerase III-specific subunits form a subcomplex with a selective function in specific transcription initiation". Genes Dev. 11 (10): 1315–26. doi:10.1101/gad.11.10.1315. PMID 9171375. 
  4. ^ Hu P, Wu S, Sun Y, Yuan CC, Kobayashi R, Myers MP, Hernandez N (Oct 2002). "Characterization of human RNA polymerase III identifies orthologues for Saccharomyces cerevisiae RNA polymerase III subunits". Mol Cell Biol. 22 (22): 8044–55. doi:10.1128/MCB.22.22.8044-8055.2002. PMC 134740Freely accessible. PMID 12391170. 
  5. ^ "Entrez Gene: POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD)". 
  6. ^ Hsieh, Y J; Wang Z; Kovelman R; Roeder R G (Jul 1999). "Cloning and characterization of two evolutionarily conserved subunits (TFIIIC102 and TFIIIC63) of human TFIIIC and their involvement in functional interactions with TFIIIB and RNA polymerase III". Mol. Cell. Biol. UNITED STATES. 19 (7): 4944–52. ISSN 0270-7306. PMC 84305Freely accessible. PMID 10373544. 
  7. ^ Hsieh, Y J; Kundu T K; Wang Z; Kovelman R; Roeder R G (Nov 1999). "The TFIIIC90 subunit of TFIIIC interacts with multiple components of the RNA polymerase III machinery and contains a histone-specific acetyltransferase activity". Mol. Cell. Biol. UNITED STATES. 19 (11): 7697–704. doi:10.1128/mcb.19.11.7697. ISSN 0270-7306. PMC 84812Freely accessible. PMID 10523658. 
  8. ^ Klopocki E, Schulze H, Strauss G, et al. (February 2007). "Complex inheritance pattern resembling autosomal recessive inheritance involving a microdeletion in thrombocytopenia-absent radius syndrome". Am. J. Hum. Genet. 80 (2): 232–40. doi:10.1086/510919. PMC 1785342Freely accessible. PMID 17236129. 

Further reading[edit]