PON2

PON2
Identifiers
Aliases	PON2, paraoxonase 2
External IDs	OMIM: 602447; MGI: 106687; HomoloGene: 385; GeneCards: PON2; OMA:PON2 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	95,435,329 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	5,298,455 bp
RNA expression pattern
	Top expressed in
	right lung; ; nucleus accumbens; ; right adrenal cortex; ; amygdala; ; putamen; ; external globus pallidus; ; jejunal mucosa; ; ventricular zone; ; left adrenal gland; ; caudate nucleus;
	Top expressed in
	epithelium of stomach; ; epithelium of lens; ; ciliary body; ; stroma of bone marrow; ; mucous cell of stomach; ; retinal pigment epithelium; ; skin of external ear; ; corneal stroma; ; ileum; ; right lung lobe;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	hydrolase activity; metal ion binding; identical protein binding; arylesterase activity; acyl-L-homoserine-lactone lactonohydrolase activity;
Cellular component	plasma membrane; lysosome; mitochondrion; nucleus; membrane; intracellular membrane-bounded organelle; extracellular region;
Biological process	aromatic compound catabolic process; response to oxidative stress; response to toxic substance; lipoxygenase pathway;
	Sources:Amigo / QuickGO
Orthologs
	5445
	330260
	ENSG00000105854
	ENSMUSG00000032667
	Q15165
	Q62086
	NM_000305; NM_001018161
	NM_183308
	NP_000296; NP_001018171
	NP_899131
	Wikidata
View/Edit Human	View/Edit Mouse

Serum paraoxonase/arylesterase 2 is an enzyme that in humans is encoded by the PON2 gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000105854 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000032667 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Primo-Parmo SL, Sorenson RC, Teiber J, La Du BN (Sep 1996). "The human serum paraoxonase/arylesterase gene (PON1) is one member of a multigene family". Genomics. 33 (3): 498–507. doi:10.1006/geno.1996.0225. PMID 8661009.
^ Mochizuki H, Scherer SW, Xi T, Nickle DC, Majer M, Huizenga JJ, Tsui LC, Prochazka M (Aug 1998). "Human PON2 gene at 7q21.3: cloning, multiple mRNA forms, and missense polymorphisms in the coding sequence". Gene. 213 (1–2): 149–57. doi:10.1016/S0378-1119(98)00193-0. PMID 9714608.
^ "Entrez Gene: PON2 paraoxonase 2".