PPFIBP1

PPFIBP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3TAD
Identifiers
Aliases	PPFIBP1, L2, SGT2, hSGT2, hSgt2p, PPFIA binding protein 1
External IDs	OMIM: 603141; MGI: 1914783; HomoloGene: 2685; GeneCards: PPFIBP1; OMA:PPFIBP1 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	27,695,564 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	146,933,523 bp
RNA expression pattern
	Top expressed in
	tendon of biceps brachii; ; sural nerve; ; buccal mucosa cell; ; epithelium of colon; ; left ovary; ; Achilles tendon; ; trigeminal ganglion; ; ventricle; ; left ventricle; ; right ventricle;
	Top expressed in
	tail of embryo; ; cumulus cell; ; hand; ; otolith organ; ; utricle; ; endothelial cell of lymphatic vessel; ; cervix; ; conjunctival fornix; ; seminal vesicula; ; semi-lunar valve;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	cadherin binding;
Cellular component	plasma membrane; focal adhesion; cytosol;
Biological process	cell adhesion;
	Sources:Amigo / QuickGO
Orthologs
	8496
	67533
	ENSG00000110841
	ENSMUSG00000016487
	Q86W92
	Q8C8U0
	NM_001198915; NM_001198916; NM_003622; NM_177444
	NM_001170433; NM_026221; NM_001355728; NM_001355729
	NP_001185844; NP_001185845; NP_003613; NP_803193
	NP_001163904; NP_080497; NP_001342657; NP_001342658
	Wikidata
View/Edit Human	View/Edit Mouse

Liprin-beta-1 is a protein that in humans is encoded by the PPFIBP1 gene.^[5]^[6]^[7]

Interactions

PPFIBP1 has been shown to interact with liprin-alpha-1.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000110841 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000016487 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b Serra-Pages C, Medley QG, Tang M, Hart A, Streuli M (Jul 1998). "Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins". J Biol Chem. 273 (25): 15611–20. doi:10.1074/jbc.273.25.15611. PMID 9624153.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ Kriajevska M, Fischer-Larsen M, Moertz E, Vorm O, Tulchinsky E, Grigorian M, Ambartsumian N, Lukanidin E (Feb 2002). "Liprin beta 1, a member of the family of LAR transmembrane tyrosine phosphatase-interacting proteins, is a new target for the metastasis-associated protein S100A4 (Mts1)". J Biol Chem. 277 (7): 5229–35. doi:10.1074/jbc.M110976200. PMID 11836260.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ "Entrez Gene: PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)".