PPIL2

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PPIL2
Protein PPIL2 PDB 1zkc.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases PPIL2, CYC4, CYP60, Cyp-60, UBOX7, hCyP-60, peptidylprolyl isomerase like 2
External IDs MGI: 2447857 HomoloGene: 8643 GeneCards: PPIL2
RNA expression pattern
PBB GE PPIL2 206064 s at fs.png

PBB GE PPIL2 209299 x at fs.png

PBB GE PPIL2 206063 x at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_014337
NM_148175
NM_148176
NM_001317996

NM_001252444
NM_001252445
NM_144954

RefSeq (protein)

NP_001304925
NP_055152
NP_680480
NP_680481

Location (UCSC) Chr 22: 21.67 – 21.7 Mb Chr 16: 17.09 – 17.11 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Peptidyl-prolyl cis-trans isomerase-like 2 is an enzyme that in humans is encoded by the PPIL2 gene.[3][4]

This gene is a member of the cyclophilin family of peptidylprolyl isomerases. The cyclophilins are a highly conserved ubiquitous family, members of which play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. This protein interacts with the proteinase inhibitor eglin c and is localized in the nucleus. Multiple transcript variants encoding different isoforms have been found for this gene.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Dunham I, Shimizu N, Roe BA, Chissoe S, Hunt AR, Collins JE, Bruskiewich R, Beare DM, Clamp M, Smink LJ, Ainscough R, Almeida JP, Babbage A, Bagguley C, Bailey J, Barlow K, Bates KN, Beasley O, Bird CP, Blakey S, Bridgeman AM, Buck D, Burgess J, Burrill WD, O'Brien KP, et al. (Dec 1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489–95. doi:10.1038/990031. PMID 10591208. 
  4. ^ a b "Entrez Gene: PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2". 

Further reading[edit]