PRCD

PRCD
Identifiers
Aliases	PRCD, RP36, progressive rod-cone degeneration, photoreceptor disc component
External IDs	OMIM: 610598; MGI: 3649529; HomoloGene: 135617; GeneCards: PRCD; OMA:PRCD - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	76,553,578 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	116,559,215 bp
RNA expression pattern
	Top expressed in
	right hemisphere of cerebellum; ; C1 segment; ; substantia nigra; ; Brodmann area 9; ; hypothalamus; ; right auricle; ; cardiac muscle tissue of right atrium; ; canal of the cervix; ; right frontal lobe; ; corpus callosum;
	Top expressed in
	neural layer of retina; ; retinal pigment epithelium; ; Epithelium of choroid plexus; ; epithelium of lens; ; iris; ; ciliary body; ; adrenal gland; ; embryo; ; ovary; ; left lung lobe;
	More reference expression data
	n/a
Gene ontology
Molecular function	opsin binding;
Cellular component	photoreceptor outer segment; cytoplasm; extracellular region; endoplasmic reticulum; Golgi apparatus; photoreceptor outer segment membrane; membrane; cell projection;
Biological process	response to stimulus; visual perception;
	Sources:Amigo / QuickGO
Orthologs
	768206
	100038570
	ENSG00000214140
	ENSMUSG00000075410
	Q00LT1
	Q00LT2
	NM_001077620
	NM_001163318
	NP_001071088
	NP_001156790
	Wikidata
View/Edit Human	View/Edit Mouse

Progressive rod-cone degeneration is a protein in humans that is encoded by the PRCD gene. ^[5]

This gene is predominantly expressed in the retina, and mutations in this gene are the cause of autosomal recessive retinal degeneration in both humans and dogs. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2010].

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000214140 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000075410 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Progressive rod-cone degeneration". Retrieved 2012-11-28.

References

Further reading