PRKX

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PRKX
Identifiers
AliasesPRKX, PKX1, protein kinase, X-linked, protein kinase X-linked
External IDsMGI: 1309999 HomoloGene: 55868 GeneCards: PRKX
Gene location (Human)
X chromosome (human)
Chr.X chromosome (human)[1]
X chromosome (human)
Genomic location for PRKX
Genomic location for PRKX
BandXp22.33Start3,604,370 bp[1]
End3,713,608 bp[1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005044

NM_016979

RefSeq (protein)

NP_005035
NP_005035.1

NP_058675

Location (UCSC)Chr X: 3.6 – 3.71 MbChr X: 77.76 – 77.8 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Protein kinase, X-linked is a protein that in humans is encoded by the PRKX gene. [5]

Function[edit]

This gene encodes a serine threonine protein kinase that has similarity to the catalytic subunit of cyclic AMP dependent protein kinases. The encoded protein is developmentally regulated and may be involved in renal epithelial morphogenesis. This protein may also be involved in macrophage and granulocyte maturation. Abnormal recombination between this gene and a related pseudogene on chromosome Y is a frequent cause of sex reversal disorder in XX males and XY females. Pseudogenes of this gene are found on chromosomes X, 15 and Y.

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000183943 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000035725 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ "Entrez Gene: Protein kinase, X-linked". Retrieved 2017-05-19.

Further reading[edit]


This article incorporates text from the United States National Library of Medicine, which is in the public domain.