PRMT2

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PRMT2
Protein PRMT2 PDB 1x2p.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases PRMT2, HRMT1L1, protein arginine methyltransferase 2
External IDs MGI: 1316652 HomoloGene: 55587 GeneCards: PRMT2
EC number 2.1.1.125
RNA expression pattern
PBB GE PRMT2 202098 s at fs.png

PBB GE PRMT2 210384 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001077638
NM_133182
NM_001302965

RefSeq (protein)

n/a

Location (UCSC) Chr 21: 46.64 – 46.67 Mb Chr 10: 76.21 – 76.24 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Protein arginine N-methyltransferase 2 is an enzyme that in humans is encoded by the PRMT2 gene.[3][4]


Interactions[edit]

PRMT2 has been shown to interact with Estrogen receptor alpha[5] and HNRPUL1.[6]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Scott HS, Antonarakis SE, Lalioti MD, Rossier C, Silver PA, Henry MF (Jun 1998). "Identification and characterization of two putative human arginine methyltransferases (HRMT1L1 and HRMT1L2)". Genomics. 48 (3): 330–40. doi:10.1006/geno.1997.5190. PMID 9545638. 
  4. ^ "Entrez Gene: PRMT2 protein arginine methyltransferase 2". 
  5. ^ Qi, Chao; Chang Jeffrey; Zhu Yiwei; Yeldandi Anjana V; Rao Sambasiva M; Zhu Yi-Jun (Aug 2002). "Identification of protein arginine methyltransferase 2 as a coactivator for estrogen receptor alpha". J. Biol. Chem. United States. 277 (32): 28624–30. doi:10.1074/jbc.M201053200. ISSN 0021-9258. PMID 12039952. 
  6. ^ Kzhyshkowska, J; Schütt H; Liss M; Kremmer E; Stauber R; Wolf H; Dobner T (Sep 2001). "Heterogeneous nuclear ribonucleoprotein E1B-AP5 is methylated in its Arg-Gly-Gly (RGG) box and interacts with human arginine methyltransferase HRMT1L1". Biochem. J. England. 358 (Pt 2): 305–14. doi:10.1042/0264-6021:3580305. ISSN 0264-6021. PMC 1222062Freely accessible. PMID 11513728. 

Further reading[edit]