PRPSAP1

PRPSAP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2C4K
Identifiers
Aliases	PRPSAP1, PAP39, phosphoribosyl pyrophosphate synthetase-associated protein 1, phosphoribosyl pyrophosphate synthetase associated protein 1
External IDs	OMIM: 601249; MGI: 1915013; HomoloGene: 55687; GeneCards: PRPSAP1; OMA:PRPSAP1 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	76,384,521 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	116,385,028 bp
RNA expression pattern
	Top expressed in
	parotid gland; ; right lobe of thyroid gland; ; gonad; ; minor salivary glands; ; left lobe of thyroid gland; ; left testis; ; right testis; ; right lung; ; ventricular zone; ; right adrenal cortex;
	Top expressed in
	Paneth cell; ; internal carotid artery; ; epithelium of lens; ; external carotid artery; ; duodenum; ; crypt of lieberkuhn of small intestine; ; endothelial cell of lymphatic vessel; ; left lobe of liver; ; condyle; ; jejunum;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	enzyme inhibitor activity; ribose phosphate diphosphokinase activity; magnesium ion binding; protein binding; identical protein binding; enzyme regulator activity;
Cellular component	ribose phosphate diphosphokinase complex; cytoplasm;
Biological process	nucleotide biosynthetic process; nucleobase-containing compound metabolic process; negative regulation of catalytic activity; 5-phosphoribose 1-diphosphate biosynthetic process; purine nucleotide biosynthetic process; regulation of catalytic activity;
	Sources:Amigo / QuickGO
Orthologs
	5635
	67763
	ENSG00000161542
	ENSMUSG00000015869
	Q14558
	Q9D0M1
	NM_002766; NM_001330503; NM_001366236
	NM_026364
	NP_001317432; NP_002757; NP_001353165
	NP_080640; NP_001391595; NP_001391596; NP_001391597; NP_001391598
	Wikidata
View/Edit Human	View/Edit Mouse

Phosphoribosyl pyrophosphate synthetase-associated protein 1 is an enzyme that in humans is encoded by the PRPSAP1 gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000161542 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000015869 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Ishizuka T, Ahmad I, Kita K, Sonoda T, Ishijima S, Sawa K, Suzuki N, Tatibana M (Jan 1997). "The human phosphoribosylpyrophosphate synthetase-associated protein 39 gene (PRPSAP1) is located in the chromosome region 17q24-q25". Genomics. 33 (2): 332–4. doi:10.1006/geno.1996.0207. PMID 8660991.
^ "Entrez Gene: PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1".

References

Further reading