PRX (gene)

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PRX
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases PRX, CMT4F, periaxin
External IDs MGI: 108176 HomoloGene: 76542 GeneCards: PRX
RNA expression pattern
PBB GE PRX 220024 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_020956
NM_181882

NM_019412
NM_198048

RefSeq (protein)

NP_066007
NP_870998

NP_062285.1
NP_932165.2
NP_062285
NP_932165

Location (UCSC) Chr 19: 40.39 – 40.41 Mb Chr 7: 27.5 – 27.52 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Periaxin is a protein that in humans is encoded by the PRX gene.[3][4][5]

The PRX gene encodes L- and S-periaxin, proteins of myelinating Schwann cells, and is mutated in Dejerine-Sottas syndrome (MIM 145900) and Charcot-Marie-Tooth disease type 4F (MIM 145900).[supplied by OMIM][5]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Gillespie CS, Sherman DL, Fleetwood-Walker SM, Cottrell DF, Tait S, Garry EM, Wallace VC, Ure J, Griffiths IR, Smith A, Brophy PJ (Jun 2000). "Peripheral demyelination and neuropathic pain behavior in periaxin-deficient mice". Neuron. 26 (2): 523–31. doi:10.1016/S0896-6273(00)81184-8. PMID 10839370. 
  4. ^ Gillespie CS, Lee M, Fantes JF, Brophy PJ (Jul 1997). "The gene encoding the Schwann cell protein periaxin localizes on mouse chromosome 7 (Prx)". Genomics. 41 (2): 297–8. doi:10.1006/geno.1997.4630. PMID 9143514. 
  5. ^ a b "Entrez Gene: PRX periaxin". 

Further reading[edit]

External links[edit]