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Prostaglandin E synthase 3 (cytosolic)
Protein PTGES3 PDB 1ejf.png
PDB rendering based on 1ejf.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols PTGES3 ; P23; TEBP; cPGES
External IDs OMIM607061 MGI1929282 HomoloGene128197 GeneCards: PTGES3 Gene
EC number
Species Human Mouse
Entrez 10728 56351
Ensembl ENSG00000110958 ENSMUSG00000071072
UniProt Q15185 Q9R0Q7
RefSeq (mRNA) NM_001282601 NM_019766
RefSeq (protein) NP_001269530 NP_062740
Location (UCSC) Chr 12:
56.66 – 56.69 Mb
Chr 10:
128.06 – 128.08 Mb
PubMed search [1] [2]

Prostaglandin E synthase 3 (cytosolic) is an enzyme that in humans is encoded by the PTGES3 gene.[1]

The protein encoded by this gene is also known as p23 which functions as a chaperone which is required for proper functioning of the glucocorticoid and other steroid receptors.[2]


  1. ^ "Entrez Gene: PTGES3 Prostaglandin E synthase 3 (cytosolic)". 
  2. ^ Freeman BC, Yamamoto KR (June 2002). "Disassembly of transcriptional regulatory complexes by molecular chaperones". Science 296 (5576): 2232–2235. doi:10.1126/science.1073051. PMID 12077419. 

Further reading[edit]