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Parkeol synthase

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Parkeol synthase
Identifiers
EC no.5.4.99.47
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
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NCBIproteins

Parkeol synthase (EC 5.4.99.47) is an enzyme with systematic name (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, parkeol-forming).[1] This enzyme catalyses the following chemical reaction

(3S)-2,3-epoxy-2,3-dihydrosqualene parkeol

The enzyme from rice (Oryza sativa) produces only parkeol.

References

  1. ^ Ito, R.; Mori, K.; Hashimoto, I.; Nakano, C.; Sato, T.; Hoshino, T. (2011). "Triterpene cyclases from Oryza sativa L.: cycloartenol, parkeol and achilleol B synthases". Org. Lett. 13: 2678–2681. doi:10.1021/ol200777d. PMID 21526825.