Peptidoglycan recognition protein 2

PGLYRP2
Identifiers
Aliases	PGLYRP2, HMFT0141, PGLYRPL, PGRP-L, PGRPL, TAGL-like, tagL, tagL-alpha, tagl-beta, peptidoglycan recognition protein 2
External IDs	OMIM: 608199; MGI: 1928099; HomoloGene: 49671; GeneCards: PGLYRP2; OMA:PGLYRP2 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	15,498,956 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	32,643,141 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; left testis; ; right testis; ; granulocyte; ; monocyte; ; blood; ; lactiferous gland; ; prostate; ; skin of abdomen; ; renal cortex;
	Top expressed in
	left lobe of liver; ; thymus; ; mesenteric lymph nodes; ; embryo; ; blood; ; spleen; ; zygote; ; pharynx; ; secondary oocyte; ; granulocyte;
	More reference expression data
	n/a
Gene ontology
Molecular function	metal ion binding; zinc ion binding; hydrolase activity; peptidoglycan immune receptor activity; peptidoglycan binding; N-acetylmuramoyl-L-alanine amidase activity;
Cellular component	intracellular anatomical structure; membrane; extracellular exosome; extracellular region; extracellular space;
Biological process	immune system process; peptide amidation; negative regulation of natural killer cell differentiation involved in immune response; negative regulation of interferon-gamma production; innate immune response; detection of bacterium; regulation of inflammatory response; defense response to Gram-positive bacterium; peptidoglycan catabolic process; pattern recognition receptor signaling pathway; antimicrobial humoral response;
	Sources:Amigo / QuickGO
Orthologs
	114770
	57757
	ENSG00000161031
	ENSMUSG00000079563
	Q96PD5
	Q8VCS0
	NM_052890; NM_001363546
	NM_001271476; NM_001271477; NM_001271478; NM_001271479; NM_021319
	NP_443122; NP_001350475
	NP_001258405; NP_001258406; NP_001258407; NP_001258408; NP_067294
	Wikidata
View/Edit Human	View/Edit Mouse

PGLYRP2 is a gene encoding a protein with N-acetylmuramoyl-L-alanine amidase activity.^[5]^[6]^[7]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000161031 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000079563 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Liu C, Xu Z, Gupta D, Dziarski R (Sep 2001). "Peptidoglycan recognition proteins: a novel family of four human innate immunity pattern recognition molecules". J Biol Chem. 276 (37): 34686–94. doi:10.1074/jbc.M105566200. PMID 11461926.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ Kibardin AV, Mirkina II, Zakeeva IR, Baranova EV, Georgiev GP, Kiselev SL (Apr 2003). "[Expression analysis of proteins encoded by genes of the tag7/tagL (PGRP-S,L) family in human peripheral blood cells]". Genetika. 39 (2): 244–9. PMID 12669421.
^ "Entrez Gene: PGLYRP2 peptidoglycan recognition protein 2".

Peptidoglycan recognition protein 2

See also

References

Further reading