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Phospholipase A2 group IVD

From Wikipedia, the free encyclopedia
PLA2G4D
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesPLA2G4D, cPLA2delta, phospholipase A2 group IVD
External IDsOMIM: 612864; MGI: 1925640; HomoloGene: 52252; GeneCards: PLA2G4D; OMA:PLA2G4D - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_178034

NM_001024137

RefSeq (protein)

NP_828848

NP_001019308

Location (UCSC)Chr 15: 42.07 – 42.09 MbChr 2: 120.1 – 120.12 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Phospholipase A2 group IVD is a protein that in humans is encoded by the PLA2G4D gene. [5]

Function

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The phospholipase A2 enzyme family, including PLA2G4D, catalyze the hydrolysis of glycerophospholipids at the sn-2 position and then liberate free fatty acids and lysophospholipids.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000159337Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000070719Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Phospholipase A2 group IVD". Retrieved 2017-09-13.
  6. ^ Chiba, H; Michibata, H; Wakimoto, K; Seishima, M; Kawasaki, S; Okubo, K; Mitsui, H; Torii, H; Imai, Y (2004). "Cloning of a gene for a novel epithelium-specific cytosolic phospholipase A2, cPLA2delta, induced in psoriatic skin". Journal of Biological Chemistry. 279 (13): 12890–7. doi:10.1074/jbc.M305801200. PMID 14709560.

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.