This article has multiple issues. Please help improve it or discuss these issues on the talk page. (Learn how and when to remove these template messages)(Learn how and when to remove this template message)
Plasma needling is a minimal invasive aesthetic medical procedure claiming to rejuvenate skin, reduce hyper- and hypotrophic scars as well as stretchmarks and to be able to reduce pattern hairloss by multimodal physical and biochemical cellular stimulation without the use of additional artificial substances. It basically is a combination of classical medical microneedling by Dermaroller or DermaPen, both used in Collagen induction therapy and PRP (platelet-rich plasma), the latter used in Prolotherapy as well as in the Vampire facelift. The stimulating effects on fibroblasts, cells and stemcells already shown in scientific publications regarding microneedling, and the injection of PRP, have also been tested as a combined treatment.
The term "plasma needling" began to emerge between the year 2013 and 2014. Despite the fact that plasma needling is already being performed in many clinics and practices, the efficacy of this technique has yet to be confirmed in large-scale controlled clinical trials.
- Fabbrocini, G; De Vita, V; Pastore, F; Annunziata, MC; Cacciapuoti, S; Monfrecola, A; Cameli, N; Tosti, A (Apr 2012). "Collagen induction therapy for the treatment of upper lip wrinkles". J Dermatolog Treat. 23 (2): 144–52. doi:10.3109/09546634.2010.544709. PMID 21810012.
- Imran Majid: Microneedling Therapy in Atrophic Facial Scars: An Objective Assessment. J Cutan Aesthet Surg. 2009 Jan-Jun; 2(1): 26–30. doi:10.4103/0974-2077.53096 PMC 2840919
- Liebl, Horst; Kloth, Luther C.; PT; MS; Fapta, CWS; Faccws (2012). "Skin Cell Proliferation Stimulated by Microneedles". J Am Coll Clin Wound Spec. 4 (1): 2–6. doi:10.1016/j.jccw.2012.11.001. PMC 3921236.
- Ramos-Torrecillas, J; Luna-Bertos Ed, Manzano-Moreno FJ; García-Martínez, O; Ruiz, C (Mar 2014). "Human fibroblast-like cultures in the presence of platelet-rich plasma as a single growth factor source: clinical implications". Adv Skin Wound Care. 27 (3): 114–20. doi:10.1097/01.ASW.0000443266.17665.19. PMID 24531517.
- Yuksel, EP; Sahin, G; Aydin, F; Senturk, N; Turanli, AY (Oct 2014). "Evaluation of effects of platelet-rich plasma on human facial skin". J Cosmet Laser Ther. 16 (5): 206–8. doi:10.3109/14764172.2014.949274. PMID 25065381.
- Cervelli, V; Garcovich, S; Bielli, A; Cervelli, G; Curcio, BC; Scioli, MG; Orlandi, A; Gentile, P (2014). "The effect of autologous activated platelet rich plasma (AA-PRP) injection on pattern hair loss: clinical and histomorphometric evaluation". Biomed Res. Int. 2014: 760709. doi:10.1155/2014/760709. PMC 4032742. PMID 24883322.
- Fabi, S; Sundaram, H (Apr 2014). "The potential of topical and injectable growth factors and cytokines for skin rejuvenation". Facial Plast Surg. 30 (2): 157–71. doi:10.1055/s-0034-1372423. PMID 24810127.
- Nofal, E; Helmy, A; Nofal, A; Alakad, R; Nasr, M (Aug 2014). "Platelet-rich plasma versus CROSS technique with 100% trichloroacetic acid versus combined skin needling and platelet rich plasma in the treatment of atrophic acne scars: a comparative study". Dermatol. Surg. 40 (8): 864–73. doi:10.1111/dsu.0000000000000091. PMID 25006854.