Q8 may refer to:
- The Kuwait Petroleum Corporation
- Q8 (New York City bus)
- Quad 8, the Quadraphonic version of Stereo 8
- Q (TV series), 4th series of Spike Milligan's TV comedy sketch show
- Pacific East Asia Cargo Airlines, IATA designator
- Trans Air Congo, IATA designator
- The usual quaternion group is denoted Q8 when one uses the notation from generalized quaternion groups
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