QSOX1

QSOX1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3LLI, 3LLK, 3Q6O, 4IJ3
Identifiers
Aliases	QSOX1, Q6, QSCN6, quiescin sulfhydryl oxidase 1
External IDs	OMIM: 603120; MGI: 1330818; HomoloGene: 37690; GeneCards: QSOX1; OMA:QSOX1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	180,204,030 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	155,688,635 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; gallbladder; ; right auricle; ; left testis; ; right testis; ; right ovary; ; upper lobe of left lung; ; left ovary; ; right lung; ; body of stomach;
	Top expressed in
	seminal vesicula; ; crypt of lieberkuhn of small intestine; ; lip; ; gallbladder; ; esophagus; ; superior surface of tongue; ; spermatocyte; ; granulocyte; ; ascending aorta; ; liver;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	oxidoreductase activity; thiol oxidase activity; protein disulfide isomerase activity; flavin-linked sulfhydryl oxidase activity;
Cellular component	integral component of membrane; integral component of Golgi membrane; Golgi membrane; Golgi apparatus; extracellular exosome; intracellular membrane-bounded organelle; membrane; intercellular bridge; extracellular region; platelet alpha granule lumen; extracellular space; specific granule lumen; tertiary granule lumen; endoplasmic reticulum lumen;
Biological process	negative regulation of macroautophagy; cell redox homeostasis; platelet degranulation; neutrophil degranulation; post-translational protein modification;
	Sources:Amigo / QuickGO
Orthologs
	5768
	104009
	ENSG00000116260
	ENSMUSG00000033684
	O00391
	Q8BND5
	NM_002826; NM_001004128
	NM_001024945; NM_023268
	NP_001004128; NP_002817
	NP_001020116; NP_075757
	Wikidata
View/Edit Human	View/Edit Mouse

Sulfhydryl oxidase 1 is an enzyme that in humans is encoded by the QSOX1 gene.^[5]^[6]^[7]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000116260 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000033684 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Coppock DL, Cina-Poppe D, Gilleran S (Feb 1999). "The quiescin Q6 gene (QSCN6) is a fusion of two ancient gene families: thioredoxin and ERV1". Genomics. 54 (3): 460–8. doi:10.1006/geno.1998.5605. PMID 9878249.
^ Coppock DL, Kopman C, Scandalis S, Gilleran S (Oct 1993). "Preferential gene expression in quiescent human lung fibroblasts". Cell Growth Differ. 4 (6): 483–93. PMID 8396966.
^ "Entrez Gene: QSCN6 quiescin Q6".

References

Further reading