RASAL2

RASAL2
Identifiers
Aliases	RASAL2, NGAP, RAS protein activator like 2
External IDs	OMIM: 606136; MGI: 2443881; HomoloGene: 35217; GeneCards: RASAL2; OMA:RASAL2 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	178,484,147 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	157,240,165 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; amniotic fluid; ; right ventricle; ; oral cavity; ; middle temporal gyrus; ; saphenous vein; ; sural nerve; ; Brodmann area 23; ; mucosa of paranasal sinus; ; tendon of biceps brachii;
	Top expressed in
	sciatic nerve; ; utricle; ; primary motor cortex; ; cingulate gyrus; ; trigeminal ganglion; ; lateral septal nucleus; ; piriform cortex; ; Temporal Lobe; ; anterior amygdaloid area; ; prefrontal cortex;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; GTPase activator activity;
Cellular component	cytoplasm; cytosol; intrinsic component of the cytoplasmic side of the plasma membrane;
Biological process	negative regulation of Ras protein signal transduction; regulation of GTPase activity; signal transduction; MAPK cascade; positive regulation of GTPase activity;
	Sources:Amigo / QuickGO
Orthologs
	9462
	226525
	ENSG00000075391
	ENSMUSG00000070565
	Q9UJF2
	n/a
	NM_004841; NM_170692
	NM_177644; NM_001401202
	NP_004832; NP_733793
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Ras GTPase-activating protein nGAP is an enzyme that in humans is encoded by the RASAL2 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000075391 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000070565 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Noto S, Maeda T, Hattori S, Inazawa J, Imamura M, Asaka M, Hatakeyama M (Jan 1999). "A novel human RasGAP-like gene that maps within the prostate cancer susceptibility locus at chromosome 1q25". FEBS Lett. 441 (1): 127–31. doi:10.1016/S0014-5793(98)01530-0. PMID 9877179.
^ "Entrez Gene: RASAL2 RAS protein activator like 2".