RDH12

RDH12
Identifiers
Aliases	RDH12, LCA13, LCA3, RP53, SDR7C2, retinol dehydrogenase 12 (all-trans/9-cis/11-cis), retinol dehydrogenase 12
External IDs	OMIM: 608830 MGI: 1925224 HomoloGene: 110830 GeneCards: RDH12
Gene location (Human)
Chr.	Chromosome 14 (human)
End	67,734,451 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	79,269,439 bp
RNA expression pattern
	Top expressed in
	vulva; ; skin of abdomen; ; gums; ; gallbladder; ; human penis; ; corpus epididymis; ; vagina; ; nipple; ; right adrenal gland; ; body of stomach;
	Top expressed in
	esophagus; ; retinal pigment epithelium; ; lip; ; secondary oocyte; ; skin of abdomen; ; skin of back; ; epidermis; ; hair follicle; ; blood; ; yolk sac;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	NAD-retinol dehydrogenase activity; oxidoreductase activity; protein binding; NADP-retinol dehydrogenase activity;
Cellular component	intracellular anatomical structure; photoreceptor inner segment membrane; photoreceptor inner segment; endoplasmic reticulum; endoplasmic reticulum membrane; membrane;
Biological process	photoreceptor cell maintenance; visual perception; retinoid metabolic process; retinol metabolic process; response to stimulus; cellular detoxification of aldehyde;
	Sources:Amigo / QuickGO
Orthologs
	145226
	77974
	ENSG00000139988
	ENSMUSG00000021123
	Q96NR8
	Q8BYK4
	NM_152443
	NM_030017; NM_001313971
	NP_689656
	NP_001300900; NP_084293
	Wikidata
View/Edit Human	View/Edit Mouse

Retinol dehydrogenase 12 is an enzyme that in humans is encoded by the RDH12 gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000139988 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000021123 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Haeseleer F, Jang GF, Imanishi Y, Driessen CA, Matsumura M, Nelson PS, Palczewski K (Nov 2002). "Dual-substrate Specificity Short Chain Retinol Dehydrogenases from the Vertebrate Retina". J Biol Chem. 277 (47): 45537–46. doi:10.1074/jbc.M208882200. PMC 1435693. PMID 12226107.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ Persson B, Kallberg Y, Bray JE, Bruford E, Dellaporta SL, Favia AD, Duarte RG, Jornvall H, Kavanagh KL, Kedishvili N, Kisiela M, Maser E, Mindnich R, Orchard S, Penning TM, Thornton JM, Adamski J, Oppermann U (Feb 2009). "The SDR (Short-Chain Dehydrogenase/Reductase and Related Enzymes) Nomenclature Initiative". Chem Biol Interact. 178 (1–3): 94–8. doi:10.1016/j.cbi.2008.10.040. PMC 2896744. PMID 19027726.
^ "Entrez Gene: RDH12 retinol dehydrogenase 12 (all-trans/9-cis/11-cis)".