RFXAP

RFXAP
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2KW3
Identifiers
Aliases	RFXAP, regulatory factor X associated protein
External IDs	OMIM: 601861; MGI: 2180854; HomoloGene: 452; GeneCards: RFXAP; OMA:RFXAP - orthologs
Gene location (Human)
Chr.	Chromosome 13 (human)
End	36,829,104 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	54,715,212 bp
RNA expression pattern
	Top expressed in
	gonad; ; tendon of biceps brachii; ; testicle; ; ventricular zone; ; palpebral conjunctiva; ; mucosa of paranasal sinus; ; gastric mucosa; ; cerebellar hemisphere; ; right hemisphere of cerebellum; ; ganglionic eminence;
	Top expressed in
	spermatocyte; ; ventricular zone; ; granulocyte; ; dentate gyrus of hippocampal formation granule cell; ; muscle of thigh; ; Paneth cell; ; thymus; ; neural layer of retina; ; right kidney; ; cerebellar cortex;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	transcription coactivator activity; DNA-binding transcription factor activity; DNA binding;
Cellular component	nucleus; nuclear speck;
Biological process	positive regulation of transcription, DNA-templated;
	Sources:Amigo / QuickGO
Orthologs
	5994
	170767
	ENSG00000133111
	ENSMUSG00000036615
	O00287
	Q8VCG9
	NM_000538
	NM_133231
	NP_000529
	NP_573494
	Wikidata
View/Edit Human	View/Edit Mouse

Regulatory factor X-associated protein is a protein that in humans is encoded by the RFXAP gene.^[5]^[6]

Template:PBB Summary

Interactions

RFXAP has been shown to interact with RFXANK.^[7]^[8]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000133111 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000036615 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Durand B, Sperisen P, Emery P, Barras E, Zufferey M, Mach B, Reith W (April 1997). "RFXAP, a novel subunit of the RFX DNA binding complex is mutated in MHC class II deficiency". EMBO J. 16 (5): 1045–55. doi:10.1093/emboj/16.5.1045. PMC 1169704. PMID 9118943.
^ "Entrez Gene: RFXAP regulatory factor X-associated protein".
^ Nekrep, N; Geyer M; Jabrane-Ferrat N; Peterlin B M (August 2001). "Analysis of ankyrin repeats reveals how a single point mutation in RFXANK results in bare lymphocyte syndrome". Mol. Cell. Biol. 21 (16). United States: 5566–76. doi:10.1128/MCB.21.16.5566-5576.2001. ISSN 0270-7306. PMC 87278. PMID 11463838. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help)
^ Nekrep, N; Jabrane-Ferrat N; Peterlin B M (June 2000). "Mutations in the bare lymphocyte syndrome define critical steps in the assembly of the regulatory factor X complex". Mol. Cell. Biol. 20 (12). UNITED STATES: 4455–61. doi:10.1128/MCB.20.12.4455-4461.2000. ISSN 0270-7306. PMC 85813. PMID 10825209. {{cite journal}}: Cite has empty unknown parameters: |laysummary=, |laydate=, and |laysource= (help)

Interactions

References

Further reading