RTKN

RTKN
Identifiers
Aliases	RTKN, rhotekin
External IDs	OMIM: 602288; MGI: 107371; HomoloGene: 7522; GeneCards: RTKN; OMA:RTKN - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	74,442,422 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	83,129,560 bp
RNA expression pattern
	Top expressed in
	C1 segment; ; right lobe of liver; ; tibial nerve; ; sural nerve; ; human kidney; ; substantia nigra; ; body of pancreas; ; inferior ganglion of vagus nerve; ; corpus callosum; ; mucosa of transverse colon;
	Top expressed in
	superior frontal gyrus; ; lip; ; primary visual cortex; ; dentate gyrus of hippocampal formation granule cell; ; internal carotid artery; ; external carotid artery; ; pontine nuclei; ; right kidney; ; lacrimal gland; ; deep cerebellar nuclei;
	More reference expression data
	n/a
Gene ontology
Molecular function	nucleotide binding; GTP binding; GTPase inhibitor activity; protein binding;
Cellular component	cytosol; cellular component; actomyosin contractile ring;
Biological process	signal transduction; apoptotic process; negative regulation of GTPase activity; regulation of apoptotic process; Rho protein signal transduction; septin cytoskeleton organization; mitotic cytokinesis; actomyosin contractile ring assembly; cortical cytoskeleton organization; septin ring organization; protein localization to mitotic actomyosin contractile ring;
	Sources:Amigo / QuickGO
Orthologs
	6242
	20166
	ENSG00000114993
	ENSMUSG00000034930
	Q9BST9
	Q8C6B2
	NM_001015055; NM_001015056; NM_033046
	NM_001136227; NM_009106; NM_133641; NM_001355524; NM_001355525
	NP_001015055; NP_001015056; NP_149035
	NP_001129699; NP_033132; NP_598396; NP_001342453; NP_001342454
	Wikidata
View/Edit Human	View/Edit Mouse

Rhotekin is a protein that in humans is encoded by the RTKN gene.^[5]^[6]^[7]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000114993 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000034930 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Jang W, Weber JS, Harkins EB, Meisler MH (May 1997). "Localization of the rhotekin gene RTKN on the physical maps of mouse chromosome 6 and human chromosome 2p13 and exclusion as a candidate for mnd2 and LGMD2B". Genomics. 40 (3): 506–7. doi:10.1006/geno.1996.4593. PMID 9073523.
^ Reynaud C, Fabre S, Jalinot P (Nov 2000). "The PDZ protein TIP-1 interacts with the Rho effector rhotekin and is involved in Rho signaling to the serum response element". J Biol Chem. 275 (43): 33962–8. doi:10.1074/jbc.M000465200. PMID 10940294.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ "Entrez Gene: RTKN rhotekin".

References

Further reading