Replication protein A3

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
RPA3
Protein RPA3 PDB 1l1o.png
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesRPA3, REPA3, RP-A p14, replication protein A3
External IDsMGI: 1915490 HomoloGene: 68285 GeneCards: RPA3
Gene location (Human)
Chromosome 7 (human)
Chr.Chromosome 7 (human)[1]
Chromosome 7 (human)
Genomic location for RPA3
Genomic location for RPA3
Band7p21.3Start7,636,518 bp[1]
End7,718,607 bp[1]
RNA expression pattern
PBB GE RPA3 209507 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002947

NM_026632

RefSeq (protein)

NP_002938

NP_080908

Location (UCSC)Chr 7: 7.64 – 7.72 MbChr 6: 8.26 – 8.26 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Replication protein A 14 kDa subunit is a protein that in humans is encoded by the RPA3 gene.[5][6]

Interactions[edit]

RPA3 has been shown to interact with replication protein A1[7][8] and replication protein A2.[7][8]

See also[edit]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000106399 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000012483 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ Umbricht CB, Erdile LF, Jabs EW, Kelly TJ (Mar 1993). "Cloning, overexpression, and genomic mapping of the 14-kDa subunit of human replication protein A". The Journal of Biological Chemistry. 268 (9): 6131–8. PMID 8454588.
  6. ^ "Entrez Gene: RPA3 replication protein A3, 14kDa".
  7. ^ a b Bochkareva E, Frappier L, Edwards AM, Bochkarev A (Feb 1998). "The RPA32 subunit of human replication protein A contains a single-stranded DNA-binding domain". The Journal of Biological Chemistry. 273 (7): 3932–6. doi:10.1074/jbc.273.7.3932. PMID 9461578.
  8. ^ a b Bochkareva E, Korolev S, Lees-Miller SP, Bochkarev A (Apr 2002). "Structure of the RPA trimerization core and its role in the multistep DNA-binding mechanism of RPA". The EMBO Journal. 21 (7): 1855–63. doi:10.1093/emboj/21.7.1855. PMC 125950. PMID 11927569.

Further reading[edit]