SEC22B

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SEC22B
Protein SEC22B PDB 1ifq.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases SEC22B, ERS-24, SEC22L1, SEC22 homolog B, vesicle trafficking protein (gene/pseudogene)
External IDs MGI: 1338759 HomoloGene: 3597 GeneCards: SEC22B
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004892

NM_011342

RefSeq (protein)

NP_004883.3
NP_004883

NP_035472.1
NP_035472

Location (UCSC) Chr 1: 120.15 – 120.18 Mb Chr 3: 97.9 – 97.92 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Vesicle-trafficking protein SEC22b is a protein that in humans is encoded by the SEC22B gene.[3][4][5]

Function[edit]

The protein encoded by this gene is a member of the SEC22 family of vesicle trafficking proteins. It seems to complex with SNARE and it is thought to play a role in the ER-Golgi protein trafficking. This protein has strong similarity to Mus musculus and Cricetulus griseus proteins. There is evidence for use of multiple polyadenylation sites for the transcript.[5] SEC22B has been shown to interact with syntaxin 18.

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Hay JC, Chao DS, Kuo CS, Scheller RH (April 1997). "Protein interactions regulating vesicle transport between the endoplasmic reticulum and Golgi apparatus in mammalian cells". Cell. 89 (1): 149–58. doi:10.1016/S0092-8674(00)80191-9. PMID 9094723. 
  4. ^ Okumura AJ, Hatsuzawa K, Tamura T, Nagaya H, Saeki K, Okumura F, Nagao K, Nishikawa M, Yoshimura A, Wada I (February 2006). "Involvement of a novel Q-SNARE, D12, in quality control of the endomembrane system". The Journal of Biological Chemistry. 281 (7): 4495–506. doi:10.1074/jbc.M509715200. PMID 16354670. 
  5. ^ a b "Entrez Gene: SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae)". 

Further reading[edit]