Jump to content

SH3GL3

From Wikipedia, the free encyclopedia
(Redirected from SH3GL3 (gene))
SH3GL3
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesSH3GL3, CNSA3, EEN-B2, HsT19371, SH3D2C, SH3P13, SH3 domain containing GRB2 like endophilin A3, SH3 domain containing GRB2 like 3, endophilin A3
External IDsOMIM: 603362; MGI: 700011; HomoloGene: 37723; GeneCards: SH3GL3; OMA:SH3GL3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001277954
NM_001277955
NM_017400

RefSeq (protein)

NP_001264883
NP_001264884
NP_059096

Location (UCSC)Chr 15: 83.45 – 83.62 MbChr 7: 82.17 – 82.31 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Endophilin-A3 is a protein that in humans is encoded by the SH3GL3 gene.[5][6]

Interactions

[edit]

SH3GL3 has been shown to interact with Huntingtin[7] and SH3KBP1.[8]

References

[edit]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000140600Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000030638Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Giachino C, Lantelme E, Lanzetti L, Saccone S, Bella Valle G, Migone N (July 1997). "A novel SH3-containing human gene family preferentially expressed in the central nervous system". Genomics. 41 (3): 427–34. doi:10.1006/geno.1997.4645. PMID 9169142.
  6. ^ "Entrez Gene: SH3GL3 SH3-domain GRB2-like 3".
  7. ^ Sittler A, Wälter S, Wedemeyer N, Hasenbank R, Scherzinger E, Eickhoff H, Bates GP, Lehrach H, Wanker EE (October 1998). "SH3GL3 associates with the Huntingtin exon 1 protein and promotes the formation of polygln-containing protein aggregates". Mol. Cell. 2 (4): 427–36. doi:10.1016/S1097-2765(00)80142-2. PMID 9809064.
  8. ^ Petrelli A, Gilestro GF, Lanzardo S, Comoglio PM, Migone N, Giordano S (March 2002). "The endophilin-CIN85-Cbl complex mediates ligand-dependent downregulation of c-Met". Nature. 416 (6877): 187–90. Bibcode:2002Natur.416..187P. doi:10.1038/416187a. PMID 11894096. S2CID 4389099.

Further reading

[edit]