SHPRH

SHPRH
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2M85, 4QN1
Identifiers
Aliases	SHPRH, bA545I5.2, SNF2 histone linker PHD RING helicase, RAD5
External IDs	OMIM: 608048; MGI: 1917581; HomoloGene: 6489; GeneCards: SHPRH; OMA:SHPRH - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	145,964,423 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	11,093,339 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; testicle; ; pancreatic epithelial cell; ; sural nerve; ; retinal pigment epithelium; ; germinal epithelium; ; gonad; ; tibia; ; skin of thigh; ; bone marrow cells;
	Top expressed in
	secondary oocyte; ; lobe of cerebellum; ; cerebellar vermis; ; primary oocyte; ; zygote; ; genital tubercle; ; lumbar subsegment of spinal cord; ; ganglionic eminence; ; trigeminal ganglion; ; ventricular zone;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; nucleotide binding; protein binding; hydrolase activity; ATP binding; helicase activity; metal ion binding; ubiquitin-protein transferase activity; ubiquitin protein ligase binding; transferase activity; ubiquitin protein ligase activity;
Cellular component	nucleosome; nucleus; nucleoplasm;
Biological process	nucleosome assembly; protein polyubiquitination; DNA repair; cellular response to DNA damage stimulus; protein ubiquitination;
	Sources:Amigo / QuickGO
Orthologs
	257218
	268281
	ENSG00000146414
	ENSMUSG00000090112
	Q149N8
	Q7TPQ3
	NM_001042683; NM_173082; NM_001370327; NM_001370328
	NM_001077707; NM_001284354; NM_172937
	NP_001036148; NP_775105; NP_001357256; NP_001357257
	NP_001071175; NP_001271283; NP_766525
	Wikidata
View/Edit Human	View/Edit Mouse

E3 ubiquitin-protein ligase SHPRH is an enzyme that in humans is encoded by the SHPRH gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000146414 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000090112 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Sood R; Makalowska I; Galdzicki M; Hu P; Eddings E; Robbins CM; Moses T; Namkoong J; Chen S; Trent JM (Jul 2003). "Cloning and characterization of a novel gene, SHPRH, encoding a conserved putative protein with SNF2/helicase and PHD-finger domains from the 6q24 region". Genomics. 82 (2): 153–61. doi:10.1016/S0888-7543(03)00121-6. PMID 12837266.
^ "Entrez Gene: SHPRH SNF2 histone linker PHD RING helicase".

References

Further reading