SLAMF6

SLAMF6
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2IF7
Identifiers
Aliases	SLAMF6, CD352, KALI, KALIb, Ly108, NTB-A, NTBA, SF2000, SLAM family member 6
External IDs	OMIM: 606446; MGI: 1353620; HomoloGene: 49945; GeneCards: SLAMF6; OMA:SLAMF6 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	160,523,262 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	171,780,737 bp
RNA expression pattern
	Top expressed in
	lymph node; ; spleen; ; appendix; ; blood; ; bone marrow cells; ; superficial temporal artery; ; gallbladder; ; rectum; ; thymus; ; upper lobe of left lung;
	Top expressed in
	thymus; ; spleen; ; lymph node; ; blood; ; submandibular gland; ; subcutaneous adipose tissue; ; bone marrow; ; white adipose tissue; ; mammary gland; ; jejunum;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding;
Cellular component	integral component of membrane; plasma membrane; extracellular exosome; membrane;
Biological process	natural killer cell proliferation; immune system process; positive regulation of interferon-gamma production; positive regulation of interleukin-17 production; innate immune response; positive regulation of natural killer cell mediated cytotoxicity; adaptive immune response; T-helper 17 cell lineage commitment; regulation of immune response; natural killer cell differentiation;
	Sources:Amigo / QuickGO
Orthologs
	114836
	30925
	ENSG00000162739
	ENSMUSG00000015314
	Q96DU3
	Q9ET39
	NM_052931; NM_001184714; NM_001184715; NM_001184716
	NM_030710; NM_001347186; NM_001347187
	NP_001171643; NP_001171644; NP_001171645; NP_443163
	NP_001334115; NP_001334116; NP_109635
	Wikidata
View/Edit Human	View/Edit Mouse

SLAM family member 6 is a protein that in humans is encoded by the SLAMF6 gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000162739 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000015314 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Bottino C, Falco M, Parolini S, Marcenaro E, Augugliaro R, Sivori S, Landi E, Biassoni R, Notarangelo LD, Moretta L, Moretta A (Aug 2001). "NTB-A [correction of GNTB-A], a novel SH2D1A-associated surface molecule contributing to the inability of natural killer cells to kill Epstein-Barr virus-infected B cells in X-linked lymphoproliferative disease". J Exp Med. 194 (3): 235–46. doi:10.1084/jem.194.3.235. PMC 2193462. PMID 11489943.
^ "Entrez Gene: SLAMF6 SLAM family member 6".

References

Further reading